Bodroux-Chichibabin aldehyde synthesis
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The Bodroux-Chichibabin aldehyde synthesis is a chemical reaction whereby a Grignard reagent is converted to an aldehyde one carbon longer.
Reaction of a Grignard reagent with triethyl orthoformate gives an acetal, which can be hydrolyzed to an aldehyde.
[edit] References
- Bodroux, F.; Compt. Rend. 1904, 138, 92.
- Chichibabin, A. E.; Ber. 1904,37, 186, 850.
- Smith, L. I. et al.; J. Org. Chem. 1941, 6, 437, 489.
