BOC (gene)

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Boc homolog (mouse)
PDB rendering based on 1x4y.
Available structures: 1x4y, 1x4z
Identifiers
Symbol(s) BOC;
External IDs OMIM: 608708 MGI: 2151153 HomoloGene: 32819
Orthologs
Human Mouse
Entrez 91653 117606
Ensembl ENSG00000144857 ENSMUSG00000022687
Uniprot Q9BWV1 Q6AZB0
Refseq NM_033254 (mRNA)
NP_150279 (protein)		 XM_001000381 (mRNA)
XP_001000381 (protein)
Location Chr 3: 114.41 - 114.49 Mb Chr 16: 44.4 - 44.48 Mb
Pubmed search [1] [2]

Boc homolog (mouse), also known as BOC, is a human gene.[1]

CDON (MIM 608707) and BOC are cell surface receptors of the immunoglobulin (Ig)/fibronectin type III (FNIII; see MIM 135600) repeat family involved in myogenic differentiation. CDON and BOC are coexpressed during development, form complexes with each other in a cis fashion, and are related to each other in their ectodomains, but each has a unique long cytoplasmic tail.[supplied by OMIM][1]

[edit] References

  1. ^ a b Entrez Gene: BOC Boc homolog (mouse).

[edit] Further reading

  • Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791-806. PMID 8889548. 
  • Kang JS, Mulieri PJ, Hu Y, et al. (2002). "BOC, an Ig superfamily member, associates with CDO to positively regulate myogenic differentiation.". EMBO J. 21 (1-2): 114-24. doi:10.1093/emboj/21.1.114. PMID 11782431. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Kang JS, Feinleib JL, Knox S, et al. (2003). "Promyogenic members of the Ig and cadherin families associate to positively regulate differentiation.". Proc. Natl. Acad. Sci. U.S.A. 100 (7): 3989-94. doi:10.1073/pnas.0736565100. PMID 12634428. 
  • Wegorzewska M, Krauss RS, Kang JS (2003). "Overexpression of the immunoglobulin superfamily members CDO and BOC enhances differentiation of the human rhabdomyosarcoma cell line RD.". Mol. Carcinog. 37 (1): 1-4. doi:10.1002/mc.10121. PMID 12720294. 
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265-70. doi:10.1101/gr.1293003. PMID 12975309. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. 
  • Kang JS, Yi MJ, Zhang W, et al. (2004). "Netrins and neogenin promote myotube formation.". J. Cell Biol. 167 (3): 493-504. doi:10.1083/jcb.200405039. PMID 15520228. 
  • Tenzen T, Allen BL, Cole F, et al. (2006). "The cell surface membrane proteins Cdo and Boc are components and targets of the Hedgehog signaling pathway and feedback network in mice.". Dev. Cell 10 (5): 647-56. doi:10.1016/j.devcel.2006.04.004. PMID 16647304. 
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