Bisphosphoglycerate phosphatase
From Wikipedia, the free encyclopedia
In enzymology, a bisphosphoglycerate phosphatase (EC 3.1.3.13) is an enzyme that catalyzes the chemical reaction
- 2,3-bisphospho-D-glycerate + H2O 3-phospho-D-glycerate + phosphate
Thus, the two substrates of this enzyme are 2,3-bisphospho-D-glycerate and H2O, whereas its two products are 3-phospho-D-glycerate and phosphate.
This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is 2,3-bisphospho-D-glycerate 2-phosphohydrolase. Other names in common use include 2,3-diphosphoglycerate phosphatase, diphosphoglycerate phosphatase, 2,3-diphosphoglyceric acid phosphatase, 2,3-bisphosphoglycerate phosphatase, and glycerate-2,3-diphosphate phosphatase. This enzyme participates in glycolysis / gluconeogenesis.
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[edit] Structural studies
As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes 1YFK, 1YJX, 2F90, 2H4X, 2H4Z, 2H52, and 2HHJ.
[edit] References
- IUBMB entry for 3.1.3.13
- BRENDA references for 3.1.3.13 (Recommended.)
- PubMed references for 3.1.3.13
- PubMed Central references for 3.1.3.13
- Google Scholar references for 3.1.3.13
- JOYCE BK, GRISOLIA S (1958). "Studies on glycerate 2,3-diphosphatase". J. Biol. Chem. 233: 350–4. PMID 13563500.
- RAPOPORT S, LUEBERING J (1951). "Glycerate-2,3-diphosphatase". J. Biol. Chem. 189: 683–94. PMID 14832286.
[edit] External links
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- The CAS registry number for this enzyme class is 9033-04-9.