Biopterin

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Biopterin
Identifiers
CAS number [22150-76-1]
PubChem 2380
MeSH Biopterin
SMILES CC(C(C1=CN=C2C(=N1) C(=O)N=C(N2)N)O)O
Properties
Molecular formula C9H11N5O3
Molar mass 237.216 g/mol
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Biopterin is a coenzyme that is produced within the body.

Defects in biopterin synthesis or regeneration can cause a form of hyperphenylalaninemia (a disease with symptoms similar to PKU) [1].

Biopterin is synthesized in several parts of the body, including the pineal gland[2].

Biopterin deficiency has been associated with a variety of disorders, including dystonia [3] and rabies[4].

[edit] References

  1. ^ Tetrahydrobiopterin
  2. ^ Biosynthesis of biopterin: adrenergic cyclic adenosine monophosphate-dependent inhibition in the pineal gland - Kapatos et al. 213 (4512): 1129 - Science
  3. ^ Dystonia with marked diurnal variation associated with biopterin deficiency - Fink et al. 38 (5): 707 - Neurology
  4. ^ Rodney E. Willoughby, Jr., "A Cure for Rabies?" Scientific American, V. 256, No. 4, April 2007, p. 95 (online link)
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