Bilirubin oxidase

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In enzymology, a bilirubin oxidase (EC 1.3.3.5) is an enzyme that catalyzes the chemical reaction

2 bilirubin + O₂ 2 biliverdin + 2 H₂O

Thus, the two substrates of this enzyme are bilirubin and O₂, whereas its two products are biliverdin and H₂O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with oxygen as acceptor. The systematic name of this enzyme class is bilirubin:oxygen oxidoreductase. This enzyme is also called bilirubin oxidase M-1. This enzyme participates in porphyrin and chlorophyll metabolism.

[edit] References

• IUBMB entry for 1.3.3.5
• BRENDA references for 1.3.3.5 (Recommended.)
• PubMed references for 1.3.3.5
• PubMed Central references for 1.3.3.5
• Google Scholar references for 1.3.3.5
• Murao S and Tanaka N (1981). "A new enzyme bilirubin oxidase produced by Myrothecium verrucaria MT-1". Agric. Biol. Chem. 45: 2383–2384. 
• Tanaka N and Murao S (1985). "Reaction of bilirubin oxidase produced by Myrothecium verrucaria MT-1. Agr". Biol. Chem. 49: 843–844. 

[edit] External links

The CAS registry number for this enzyme class is 80619-01-8.

• IUBMB entry for 1.3.3.5

• KEGG entry for 1.3.3.5

• BRENDA entry for 1.3.3.5

• NiceZyme view of 1.3.3.5

• EC2PDB: PDB structures for 1.3.3.5

• PRIAM entry for 1.3.3.5

• PUMA2 entry for 1.3.3.5

• IntEnz: Integrated Enzyme entry for 1.3.3.5

• MetaCyc entry for 1.3.3.5

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047705: bilirubin oxidase

• AMIGO entry for GO code 0047705: bilirubin oxidase