Bilirubin-glucuronoside glucuronosyltransferase

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In enzymology, a bilirubin-glucuronoside glucuronosyltransferase (EC 2.4.1.95) is an enzyme that catalyzes the chemical reaction

2 bilirubin-glucuronoside bilirubin + bilirubin-bisglucuronoside

Hence, this enzyme has one substrate, bilirubin-glucuronoside, and two products, bilirubin and bilirubin-bisglucuronoside.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is bilirubin-glucuronoside:bilirubin-glucuronoside D-glucuronosyltransferase. Other names in common use include bilirubin monoglucuronide transglucuronidase, and bilirubin glucuronoside glucuronosyltransferase.

[edit] References

• IUBMB entry for 2.4.1.95
• BRENDA references for 2.4.1.95 (Recommended.)
• PubMed references for 2.4.1.95
• PubMed Central references for 2.4.1.95
• Google Scholar references for 2.4.1.95
• Jansen PL, Chowdhury JR, Fischberg EB, Arias IM (1977). "Enzymatic conversion of bilirubin monoglucuronide to diglucuronide by rat liver plasma membranes". J. Biol. Chem. 252: 2710–6. PMID 15996. 

[edit] External links

The CAS registry number for this enzyme class is 71822-22-5.

• IUBMB entry for 2.4.1.95

• KEGG entry for 2.4.1.95

• BRENDA entry for 2.4.1.95

• NiceZyme view of 2.4.1.95

• EC2PDB: PDB structures for 2.4.1.95

• PRIAM entry for 2.4.1.95

• PUMA2 entry for 2.4.1.95

• IntEnz: Integrated Enzyme entry for 2.4.1.95

• MetaCyc entry for 2.4.1.95

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047278: bilirubin-glucuronoside glucuronosyltransferase

• AMIGO entry for GO code 0047278: bilirubin-glucuronoside glucuronosyltransferase