Bile-acid-CoA hydrolase

From Wikipedia, the free encyclopedia

In enzymology, a bile-acid-CoA hydrolase (EC 3.1.2.26) is an enzyme that catalyzes the chemical reaction

deoxycholoyl-CoA + H₂O CoA + deoxycholate

Thus, the two substrates of this enzyme are deoxycholoyl-CoA and H₂O, whereas its two products are CoA and deoxycholate.

This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is deoxycholoyl-CoA hydrolase.

[edit] References

• IUBMB entry for 3.1.2.26
• BRENDA references for 3.1.2.26 (Recommended.)
• PubMed references for 3.1.2.26
• PubMed Central references for 3.1.2.26
• Google Scholar references for 3.1.2.26
• Ye HQ, Mallonee DH, Wells JE, Bjorkhem I, Hylemon PB (1999). "The bile acid-inducible baiF gene from Eubacterium sp. strain VPI 12708 encodes a bile acid-coenzyme A hydrolase". J. Lipid. Res. 40: 17–23. PMID 9869646. 

[edit] External links

• IUBMB entry for 3.1.2.26

• KEGG entry for 3.1.2.26

• BRENDA entry for 3.1.2.26

• NiceZyme view of 3.1.2.26

• EC2PDB: PDB structures for 3.1.2.26

• PRIAM entry for 3.1.2.26

• PUMA2 entry for 3.1.2.26

• IntEnz: Integrated Enzyme entry for 3.1.2.26

• MetaCyc entry for 3.1.2.26

• Atomic-resolution structures of enzymes belonging to this class