Bicinchoninic acid

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Bicinchoninic acid
IUPAC name 2-(4-carboxyquinolin-2-yl)quinoline-4-carboxylic acid
Other names Bicinchoninic acid
4,4'-Dicarboxy-2,2'-Biquinoline
Identifiers
CAS number [1245-13-2]
Properties
Molecular formula (HO2CC9H5N)2
Molar mass 344.33 g/mol
Appearance Cream powder. Characteristic odor.
Density Solid in pure form.
Density not available.
Melting point

365 to 367 °C

Boiling point

Not available.

Solubility in water Partially soluble in cold water, hot water.
Hazards
MSDS External MSDS
Main hazards Will irritate eyes and mucous membranes.
The chemical, physical and toxicological
properties have not been fully investigated.
Presume moderate toxicity internally. LD/TD
no data. OSHA PEL/ACGIH TLV not established.
No evidence of carcinogenicity.
NFPA 704
 
 
 
 
Flash point N/A
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Bicinchoninic acid is a weak acid composed of two carboxylated quinoline rings.

Bicinchoninic acid is most commonly employed by biochemists in the bicinchoninic acid assay, which is used to determine the total level of protein in a solution. In this assay, two molecules of bicinchoninic acid chelate a single Cu1+ ion, forming a purple water-soluble complex that strongly aborbs light at 562 nm.

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