BEX2

From Wikipedia, the free encyclopedia


Brain expressed X-linked 2
Identifiers
Symbol(s) BEX2; BEX1; DJ79P11.1
External IDs HomoloGene88940
Orthologs
Human Mouse
Entrez 84707 n/a
Ensembl ENSG00000133134 n/a
Uniprot Q9BXY8 n/a
Refseq NM_032621 (mRNA)
NP_116010 (protein)
n/a (mRNA)
n/a (protein)
Location Chr X: 102.45 - 102.45 Mb n/a
Pubmed search [1] n/a

Brain expressed X-linked 2, also known as BEX2, is a human gene.[1]


[edit] References

[edit] Further reading

  • Baldisseri DM, Margolis JW, Weber DJ, et al. (2002). "Olfactory marker protein (OMP) exhibits a beta-clam fold in solution: implications for target peptide interaction and olfactory signal transduction.". J. Mol. Biol. 319 (3): 823-37. doi:10.1016/S0022-2836(02)00282-6. PMID 12054873. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome.". Nature 434 (7031): 325-37. doi:10.1038/nature03440. PMID 15772651. 
  • Alvarez E, Zhou W, Witta SE, Freed CR (2005). "Characterization of the Bex gene family in humans, mice, and rats.". Gene 357 (1): 18-28. doi:10.1016/j.gene.2005.05.012. PMID 15958283. 
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514. 
  • Han C, Liu H, Liu J, et al. (2005). "Human Bex2 interacts with LMO2 and regulates the transcriptional activity of a novel DNA-binding complex.". Nucleic Acids Res. 33 (20): 6555-65. doi:10.1093/nar/gki964. PMID 16314316. 
  • Foltz G, Ryu GY, Yoon JG, et al. (2006). "Genome-wide analysis of epigenetic silencing identifies BEX1 and BEX2 as candidate tumor suppressor genes in malignant glioma.". Cancer Res. 66 (13): 6665-74. doi:10.1158/0008-5472.CAN-05-4453. PMID 16818640. 
  • Fischer C, Drexler HG, Reinhardt J, et al. (2007). "Epigenetic regulation of brain expressed X-linked-2, a marker for acute myeloid leukemia with mixed lineage leukemia rearrangements.". Leukemia 21 (2): 374-7. doi:10.1038/sj.leu.2404493. PMID 17251904. 
  • Naderi A, Teschendorff AE, Beigel J, et al. (2007). "BEX2 is overexpressed in a subset of primary breast cancers and mediates nerve growth factor/nuclear factor-kappaB inhibition of apoptosis in breast cancer cell lines.". Cancer Res. 67 (14): 6725-36. doi:10.1158/0008-5472.CAN-06-4394. PMID 17638883.