Beta-apiosyl-beta-glucosidase

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In enzymology, a beta-apiosyl-beta-glucosidase (EC 3.2.1.161) is an enzyme that catalyzes the chemical reaction

7-[beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranosyloxy]isoflavonoid + H₂O $\rightleftharpoons$ a 7-hydroxyisoflavonoid + beta-D-apiofuranosyl-(1->6)-D-glucose

The 3 substrates of this enzyme are [[7-[beta-D-apiofuranosyl-(1->6)-beta-D-]], [[glucopyranosyloxy]isoflavonoid]], and H₂O, whereas its two products are 7-hydroxyisoflavonoid and [[beta-D-apiofuranosyl-(1->6)-D-glucose]].

This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is 7-[beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranosyloxy]isoflavonoid beta-D-apiofuranosyl-(1->6)-D-glucohydrolase. Other names in common use include isoflavonoid-7-O-beta[D-apiosyl-(1->6)-beta-D-glucoside], disaccharidase, isoflavonoid 7-O-beta-apiosyl-glucoside beta-glucosidase, and furcatin hydrolase.

[edit] References

IUBMB entry for 3.2.1.161
BRENDA references for 3.2.1.161 (Recommended.)
PubMed references for 3.2.1.161
PubMed Central references for 3.2.1.161
Google Scholar references for 3.2.1.161
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Cairns JR (2005). "Purification of an isoflavonoid 7-O-beta-apiosyl-glucoside beta-glycosidase and its substrates from Dalbergia nigrescens Kurz". Phytochemistry. 66: 1880–9. doi:10.1016/j.phytochem.2005.06.024. PMID 16098548.
Ahn YO, Mizutani M, Saino H, Sakata K (2004). "Furcatin hydrolase from Viburnum furcatum Blume is a novel disaccharide-specific acuminosidase in glycosyl hydrolase family 1". J. Biol. Chem. 279: 23405–14. doi:10.1074/jbc.M311379200. PMID 14976214.