Beta-alanyl-CoA ammonia-lyase

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In enzymology, a beta-alanyl-CoA ammonia-lyase (EC 4.3.1.6) is an enzyme that catalyzes the chemical reaction

beta-alanyl-CoA acryloyl-CoA + NH₃

Hence, this enzyme has one substrate, beta-alanyl-CoA, and two products, acryloyl-CoA and NH₃.

This enzyme belongs to the family of lyases, specifically ammonia lyases, which cleave carbon-nitrogen bonds. The systematic name of this enzyme class is beta-alanyl-CoA ammonia-lyase (acryloyl-CoA-forming). This enzyme is also called beta-alanyl coenzyme A ammonia-lyase. This enzyme participates in beta-alanine metabolism and propanoate metabolism.

[edit] References

• IUBMB entry for 4.3.1.6
• BRENDA references for 4.3.1.6 (Recommended.)
• PubMed references for 4.3.1.6
• PubMed Central references for 4.3.1.6
• Google Scholar references for 4.3.1.6
• Stadtman ER (1955). "The enzymic synthesis of beta-alanyl coenzyme A". J. Am. Chem. Soc. 77: 5765–5766. doi:10.1021/ja01626a108. 

[edit] External links

The CAS registry number for this enzyme class is 9024-29-7.

• IUBMB entry for 4.3.1.6

• KEGG entry for 4.3.1.6

• BRENDA entry for 4.3.1.6

• NiceZyme view of 4.3.1.6

• EC2PDB: PDB structures for 4.3.1.6

• PRIAM entry for 4.3.1.6

• PUMA2 entry for 4.3.1.6

• IntEnz: Integrated Enzyme entry for 4.3.1.6

• MetaCyc entry for 4.3.1.6

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047698: beta-alanyl-CoA ammonia-lyase

• AMIGO entry for GO code 0047698: beta-alanyl-CoA ammonia-lyase