Benzoin aldolase

From Wikipedia, the free encyclopedia

In enzymology, a benzoin aldolase (EC 4.1.2.38) is an enzyme that catalyzes the chemical reaction

2-hydroxy-1,2-diphenylethanone 2 benzaldehyde

Hence, this enzyme has one substrate, 2-hydroxy-1,2-diphenylethanone, and one product, benzaldehyde.

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase (benzaldehyde-forming). Other names in common use include benzaldehyde lyase, and 2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase. It employs one cofactor, thiamin diphosphate.

Contents 1 Structural studies 2 References 3 External links 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes 2AG0, 2AG1, and 2UZ1.

[edit] References

• IUBMB entry for 4.1.2.38
• BRENDA references for 4.1.2.38 (Recommended.)
• PubMed references for 4.1.2.38
• PubMed Central references for 4.1.2.38
• Google Scholar references for 4.1.2.38
• Gonzalez B, Vicuna R (1989). "Benzaldehyde lyase, a novel thiamine PPi-requiring enzyme, from Pseudomonas fluorescens biovar I". J. Bacteriol. 171: 2401–5. PMID 2496105. 

[edit] External links

The CAS registry number for this enzyme class is 122097-01-2.

• IUBMB entry for 4.1.2.38

• KEGG entry for 4.1.2.38

• BRENDA entry for 4.1.2.38

• NiceZyme view of 4.1.2.38

• EC2PDB: PDB structures for 4.1.2.38

• PRIAM entry for 4.1.2.38

• PUMA2 entry for 4.1.2.38

• IntEnz: Integrated Enzyme entry for 4.1.2.38

• MetaCyc entry for 4.1.2.38

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047695: benzoin aldolase

• AMIGO entry for GO code 0047695: benzoin aldolase