Benzaldehyde dehydrogenase (NAD+)

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In enzymology, a benzaldehyde dehydrogenase (NAD+) (EC 1.2.1.28) is an enzyme that catalyzes the chemical reaction

benzaldehyde + NAD⁺ + H₂O benzoate + NADH + 2 H⁺

The 3 substrates of this enzyme are benzaldehyde, NAD⁺, and H₂O, whereas its 3 products are benzoate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is benzaldehyde:NAD+ oxidoreductase. Other names in common use include benzaldehyde (NAD+) dehydrogenase, and benzaldehyde dehydrogenase (NAD+). This enzyme participates in benzoate degradation via hydroxylation and toluene and xylene degradation.

[edit] References

• IUBMB entry for 1.2.1.28
• BRENDA references for 1.2.1.28 (Recommended.)
• PubMed references for 1.2.1.28
• PubMed Central references for 1.2.1.28
• Google Scholar references for 1.2.1.28
• GUNSALUS CF, STANIER RY, GUNSALUS IC (1953). "The enzymatic conversion of mandelic acid to benzoic acid. III Fractionation and properties of the soluble enzymes". J. Bacteriol. 66: 548–53. PMID 13108854. 

[edit] External links

The CAS registry number for this enzyme class is 37250-93-4.

• IUBMB entry for 1.2.1.28

• KEGG entry for 1.2.1.28

• BRENDA entry for 1.2.1.28

• NiceZyme view of 1.2.1.28

• EC2PDB: PDB structures for 1.2.1.28

• PRIAM entry for 1.2.1.28

• PUMA2 entry for 1.2.1.28

• IntEnz: Integrated Enzyme entry for 1.2.1.28

• MetaCyc entry for 1.2.1.28

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0018479: benzaldehyde dehydrogenase (NAD+)

• AMIGO entry for GO code 0018479: benzaldehyde dehydrogenase (NAD+)