Bemegride
From Wikipedia, the free encyclopedia
 |
|
|
Bemegride
|
|
| Systematic (IUPAC) name | |
| 4-Ethyl-4-methyl-2,6-piperidinedione | |
| Identifiers | |
| CAS number | |
| ATC code | R07 |
| PubChem | |
| Chemical data | |
| Formula | C8H13NO2 |
| Mol. mass | 155.2 g/mol |
| Synonyms | Methetharimide β,β-methylethylglutarimide |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | ? |
Bemegride (also known as Megimide) is a Central Nervous System stimulant and antidote for barbiturate poisoning. As a stimulant it is approximately as potent as phendimetrazine or pemoline.
[edit] John Bodkin Adams case
-
For more details on this topic, see John Bodkin Adams#Gertrude Hullett.
Bemegride is notable in legal history as the drug suspected serial killer Dr John Bodkin Adams failed to prescribe correctly to his patient Gertrude Hullett. Hullett took an overdose of barbiturates on 19 July 1956 but Adams only gave her a single 10cc dose of Bemigride three days later on the 22nd, despite having acquired 100cc for her treatment. Hullett died the next day on 23 July 1956. Adams was charged but never tried for her murder.[1]
[edit] Animal use
Bemigride is also used to induce convulsions in experimental animals.[2]
[edit] References
- ^ Cullen, Pamela V., A Stranger in Blood: The Case Files on Dr John Bodkin Adams, London, Elliott & Thompson, 2006, ISBN 1-904027-19-9
- ^ http://cancerweb.ncl.ac.uk/cgi-bin/omd?bemegride
 |
This pharmacology-related article is a stub. You can help Wikipedia by expanding it. |
|
|||||||||||
