Befuraline

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Befuraline is a piperazine derivative drug invented in Germany in the 1970s. [1] Befuraline has stimulant and antidepressant effects and has seen some use in Germany and France, although it has never become widely used. [2] Befuraline has an active metabolite benzylpiperazine, which is responsible for its stimulant effects.

Image:Befuraline.png

1-(2-Benzofuranylcarbonyl)-4-benzylpiperazine

CAS# 41716-84-1; 41717-30-0

[edit] References

  1. ^ Boksay IJ, Popendiker K, Weber RO, Soder A. Synthesis and pharmacological activity of befuraline (N-benzo[b]furan-2-ylcarbonyl-N'-benzylpiperazine), a new antidepressant compound. Arzneimittel-Forschung. 1979;29(2):193-204.
  2. ^ Gastpar M, Gastpar G, Gilsdorf U. Befuraline, its safety and efficacy in depressed inpatients. Pharmacopsychiatry. 1985 Nov;18(6):351-5.