Bcl-2 homologous antagonist killer

From Wikipedia, the free encyclopedia

The Bcl-2 homologous antagonist/killer (BAK) protein is a pro-apoptotic member of the Bcl-2 gene family which is involved in initiating apoptosis. It has a relative molecular weight of 23,400 and contain 211-amino acids. Dysregulation of the BAK gene has been implicated in human gastrointestinal cancers, indicating that the gene plays a part in the pathogenesis of some cancers[1].

[edit] See also

[edit] References

  1. ^ Qiang-Song Tong, et al. (2004). "BAK overexpression mediates p53-independent apoptosis inducing effects on human gastric cancer cells". BMC Cancer 4 (33): 33. doi:10.1186/1471-2407-4-33. 
 This molecular biology article is a stub. You can help Wikipedia by expanding it.