BCL2L13

From Wikipedia, the free encyclopedia

BCL2-like 13 (apoptosis facilitator)

Identifiers

BCL2L13; BCL-RAMBO; MIL1

External IDs

Gene ontology
Molecular Function:	• caspase activator activity
Cellular Component:	• mitochondrion • membrane • integral to membrane
Biological Process:	• induction of apoptosis • caspase activation • regulation of apoptosis

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_015367 (mRNA)
NP_056182 (protein)

NM_153516 (mRNA)
NP_705736 (protein)

Location

Chr 22: 16.5 - 16.59 Mb

Chr 6: 120.8 - 120.86 Mb

Pubmed search

[1]

[2]

BCL2-like 13 (apoptosis facilitator), also known as BCL2L13, is a human gene.^[1]

[edit] References

^ Entrez Gene: BCL2L13 BCL2-like 13 (apoptosis facilitator).

[edit] Further reading

Dunham I, Shimizu N, Roe BA, et al. (1999). "The DNA sequence of human chromosome 22.". Nature 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208.
Kataoka T, Holler N, Micheau O, et al. (2001). "Bcl-rambo, a novel Bcl-2 homologue that induces apoptosis via its unique C-terminal extension.". J. Biol. Chem. 276 (22): 19548–54. doi:10.1074/jbc.M010520200. PMID 11262395.
Footz TK, Brinkman-Mills P, Banting GS, et al. (2001). "Analysis of the cat eye syndrome critical region in humans and the region of conserved synteny in mice: a search for candidate genes at or near the human chromosome 22 pericentromere.". Genome Res. 11 (6): 1053–70. doi:10.1101/gr.154901. PMID 11381032.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Yi P, Zhang W, Zhai Z, et al. (2004). "Bcl-rambo beta, a special splicing variant with an insertion of an Alu-like cassette, promotes etoposide- and Taxol-induced cell death.". FEBS Lett. 534 (1-3): 61–8. PMID 12527362.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Collins JE, Wright CL, Edwards CA, et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome.". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMID 15461802.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Banga S, Gao P, Shen X, et al. (2007). "Legionella pneumophila inhibits macrophage apoptosis by targeting pro-death members of the Bcl2 protein family.". Proc. Natl. Acad. Sci. U.S.A. 104 (12): 5121–6. doi:10.1073/pnas.0611030104. PMID 17360363.