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The Battle of Resaena or Resaina, near Ceylanpinar TR, was fought in 243 between the forces of the Roman Empire, led by Praetorian Prefect Timesitheus, and a Sassanid Empire army, led by King Shapur I. The Romans were victorious.
The battle was fought during a campaign ordered by Emperor Gordian III to retake the Roman cities of Hatra, Nisibis and Carrhae. These territories, in fact, had been conquered by Shapur and, before him, by his father King Ardashir I, when the Roman Empire was plagued with the internal wars between pretenders to the throne.