BASP1

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Brain abundant, membrane attached signal protein 1
Identifiers
Symbol(s) BASP1; CAP-23; CAP23; MGC8555; NAP-22; NAP22
External IDs OMIM: 605940 MGI: 1917600 HomoloGene: 38168
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 10409 70350
Ensembl ENSG00000176788 ENSMUSG00000045763
Uniprot P80723 Q91XV3
Refseq NM_006317 (mRNA)
NP_006308 (protein)		 XM_979955 (mRNA)
XP_985049 (protein)
Location Chr 5: 17.27 - 17.33 Mb Chr 15: 25.31 - 25.36 Mb
Pubmed search [1] [2]

Brain abundant, membrane attached signal protein 1, also known as BASP1, is a human gene.[1]

This gene encodes a membrane bound protein with several transient phosphorylation sites and PEST motifs. Conservation of proteins with PEST sequences among different species supports their functional significance. PEST sequences typically occur in proteins with high turnover rates. Immunological characteristics of this protein are species specific. This protein also undergoes N-terminal myristoylation.[1]

[edit] References

  1. ^ a b Entrez Gene: BASP1 brain abundant, membrane attached signal protein 1.

[edit] Further reading

  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635-48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Carpenter B, Hill KJ, Charalambous M, et al. (2004). "BASP1 is a transcriptional cosuppressor for the Wilms' tumor suppressor protein WT1.". Mol. Cell. Biol. 24 (2): 537-49. PMID 14701728. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Fitzgibbon J, Neat MJ, Foot N, et al. (2000). "Assignment of brain acid-soluble protein 1 (BASP1) to human chromosome 5p15.1-->p14, differential expression in human cancer cell lines as a result of alterations in gene dosage.". Cytogenet. Cell Genet. 89 (3-4): 147-9. PMID 10965107. 
  • Park S, Kim YI, Kim B, et al. (1998). "Characterization of bovine and human cDNAs encoding NAP-22 (22 kDa neuronal tissue-enriched acidic protein) homologs.". Mol. Cells 8 (4): 471-7. PMID 9749536. 
  • Mosevitsky MI, Capony JP, Skladchikova GYu, et al. (1997). "The BASP1 family of myristoylated proteins abundant in axonal termini. Primary structure analysis and physico-chemical properties.". Biochimie 79 (6): 373-84. PMID 9310187. 
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