B3GALTL

From Wikipedia, the free encyclopedia

Beta 1,3-galactosyltransferase-like

Identifiers

B3GALTL; B3GTL; B3Glc-T; Gal-T

External IDs

OMIM: 610308 MGI: 2685903 HomoloGene: 14978

Gene ontology
Molecular Function:	• transferase activity, transferring glycosyl groups
Cellular Component:	• endoplasmic reticulum • membrane • integral to membrane
Biological Process:	• carbohydrate metabolic process • fucose metabolic process

Orthologs

Human

Mouse

Refseq

NM_194318 (mRNA)
NP_919299 (protein)

XM_355669 (mRNA)
XP_355669 (protein)

Location

Chr 13: 30.67 - 30.8 Mb

Chr 5: 149.95 - 150.03 Mb

Pubmed search

[1]

[2]

Beta 1,3-galactosyltransferase-like, also known as B3GALTL, is a human gene.^[1]

[edit] References

^ Entrez Gene: B3GALTL beta 1,3-galactosyltransferase-like.

[edit] Further reading

Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Heinonen TY, Pasternack L, Lindfors K, et al. (2003). "A novel human glycosyltransferase: primary structure and characterization of the gene and transcripts.". Biochem. Biophys. Res. Commun. 309 (1): 166–74. PMID 12943678.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Dunham A, Matthews LH, Burton J, et al. (2004). "The DNA sequence and analysis of human chromosome 13.". Nature 428 (6982): 522–8. doi:10.1038/nature02379. PMID 15057823.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.
Sato T, Sato M, Kiyohara K, et al. (2007). "Molecular cloning and characterization of a novel human beta1,3-glucosyltransferase, which is localized at the endoplasmic reticulum and glucosylates O-linked fucosylglycan on thrombospondin type 1 repeat domain.". Glycobiology 16 (12): 1194–206. doi:10.1093/glycob/cwl035. PMID 16899492.
Lesnik Oberstein SA, Kriek M, White SJ, et al. (2006). "Peters Plus syndrome is caused by mutations in B3GALTL, a putative glycosyltransferase.". Am. J. Hum. Genet. 79 (3): 562–6. doi:10.1086/507567. PMID 16909395.
Kozma K, Keusch JJ, Hegemann B, et al. (2007). "Identification and characterization of abeta1,3-glucosyltransferase that synthesizes the Glc-beta1,3-Fuc disaccharide on thrombospondin type 1 repeats.". J. Biol. Chem. 281 (48): 36742–51. doi:10.1074/jbc.M605912200. PMID 17032646.