Avenanthramide

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Avenanthramides are a type of oat phytoalexins that exist predominantly in the groats of oat seeds.[1]

Among a group of at least 25 avenanthramides[2] that differ in the substituents on the cinnamic acid and anthranilic acid rings, three are predominant in oat grain: Bc (also called avenanthramide C), Bf (also called avenanthramide B) and Bp (also called avenanthramide A).

In vitro experiments indicate that they have significant antioxidant activities, with Bc > Bf > Bp.[3] In human and animal tests, this antioxidant capacity provides health benefits ranging from reduced rate of LDL oxidation[4] to protecting against cancers and heart disease.[5]

[edit] Notes

  1. ^ Emmons, C. L. & Peterson, D. M. (1999) Antioxidant activity and phenolic contents of oat groats and hulls. Cereal Chem. 76:902-906.
  2. ^ 2. Collins, F. W. (1989) Oat phenolics: avenanthramides, novel substituted N-cinnamoylanthranilate alkaloids from oat groats and hulls. J. Agric. Food Chem. 37:60-66.
  3. ^ Peterson D.M.1; Hahn M.J.; Emmons C.L.(2002) Oat Avenanthramides Exhibit Antioxidant Activities In Vitro. Food Chem. 79:4:473-478
  4. ^ Chen, C.Y & Blumberg , J. B. (2004) Vitamin C to Enhance Hamster and Human LDL Resistance to Oxidation J. Nutr. 134:1459-1466
  5. ^ Bailey, G.S. & Williams, D.E.(1993) Potential Mechanisms for Food-Related Carcinogens and Anticarcinogens. Food Technol. 47:105-118


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