ATP adenylyltransferase

From Wikipedia, the free encyclopedia

In enzymology, an ATP adenylyltransferase (EC 2.7.7.53) is an enzyme that catalyzes the chemical reaction

ADP + ATP phosphate + P₁,P₄-bis(5'-adenosyl) tetraphosphate

Thus, the two substrates of this enzyme are ADP and ATP, whereas its two products are phosphate and P1,P4-bis(5'-adenosyl) tetraphosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is ADP:ATP adenylyltransferase. Other names in common use include bis(5'-nucleosyl)-tetraphosphate phosphorylase (NDP-forming), diadenosinetetraphosphate alphabeta-phosphorylase, adenine triphosphate adenylyltransferase, diadenosine 5',5'"-P1,P4-tetraphosphate alphabeta-phosphorylase, (ADP-forming), and dinucleoside oligophosphate alphabeta-phosphorylase. This enzyme participates in purine metabolism.

[edit] References

• IUBMB entry for 2.7.7.53
• BRENDA references for 2.7.7.53 (Recommended.)
• PubMed references for 2.7.7.53
• PubMed Central references for 2.7.7.53
• Google Scholar references for 2.7.7.53
• Guranowski A, Blanquet S (1985). "Phosphorolytic cleavage of diadenosine 5',5-P1,P4-tetraphosphate Properties of homogeneous diadenosine 5',5-P1,P4-tetraphosphate alpha, beta-phosphorylase from Saccharomyces cerevisiae". J. Biol. Chem. 260: 3542–7. PMID 2982863. 

[edit] External links

The CAS registry number for this enzyme class is 96697-71-1.

• IUBMB entry for 2.7.7.53

• KEGG entry for 2.7.7.53

• BRENDA entry for 2.7.7.53

• NiceZyme view of 2.7.7.53

• EC2PDB: PDB structures for 2.7.7.53

• PRIAM entry for 2.7.7.53

• PUMA2 entry for 2.7.7.53

• IntEnz: Integrated Enzyme entry for 2.7.7.53

• MetaCyc entry for 2.7.7.53

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0003877: ATP adenylyltransferase

• AMIGO entry for GO code 0003877: ATP adenylyltransferase