ATP6V0A2

From Wikipedia, the free encyclopedia

ATPase, H+ transporting, lysosomal V0 subunit a2

Identifiers

ATP6V0A2; Stv1; Vph1; ATP6N1D; ATP6a2; J6B7; TJ6; TJ6M; TJ6s; a2

External IDs

Gene ontology
Molecular Function:	• protein binding • hydrogen ion transmembrane transporter activity
Cellular Component:	• acrosome • membrane • integral to membrane
Biological Process:	• ion transport • immune response • proton transport

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_012463 (mRNA)
NP_036595 (protein)

NM_011596 (mRNA)
NP_035726 (protein)

Location

Chr 12: 122.76 - 122.81 Mb

Chr 5: 124.89 - 125.01 Mb

Pubmed search

[1]

[2]

ATPase, H+ transporting, lysosomal V0 subunit a2, also known as ATP6V0A2, is a human gene.^[1]

[edit] References

^ Entrez Gene: ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2.

[edit] Further reading

Nishi T, Forgac M (2002). "The vacuolar (H+)-ATPases--nature's most versatile proton pumps.". Nat. Rev. Mol. Cell Biol. 3 (2): 94-103. doi:10.1038/nrm729. PMID 11836511.
Kawasaki-Nishi S, Nishi T, Forgac M (2003). "Proton translocation driven by ATP hydrolysis in V-ATPases.". FEBS Lett. 545 (1): 76-85. PMID 12788495.
Morel N (2004). "Neurotransmitter release: the dark side of the vacuolar-H+ATPase.". Biol. Cell 95 (7): 453-7. PMID 14597263.
Lee C, Ghoshal K, Beaman KD (1991). "Cloning of a cDNA for a T cell produced molecule with a putative immune regulatory role.". Mol. Immunol. 27 (11): 1137-44. PMID 2247090.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Smith AN, Lovering RC, Futai M, et al. (2003). "Revised nomenclature for mammalian vacuolar-type H+ -ATPase subunit genes.". Mol. Cell 12 (4): 801-3. PMID 14580332.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Derks R, Beaman K (2005). "Regeneration and tolerance factor modulates the effect of adenosine triphosphate-induced interleukin 1 beta secretion in human macrophages.". Hum. Immunol. 65 (7): 676-82. doi:10.1016/j.humimm.2004.04.006. PMID 15301855.
Derks RA, Beaman KD (2005). "Regeneration and tolerance factor prevents bystander T-cell death associated with human immunodeficiency virus infection.". Clin. Diagn. Lab. Immunol. 11 (5): 835-40. doi:10.1128/CDLI.11.5.835-840.2004. PMID 15358640.
Lattuada D, Mangioni S, Viganò P, et al. (2005). "The placental immunomodulatory cytokine regeneration and tolerance factor is also expressed by both human cycling and early pregnant endometrium.". Am. J. Reprod. Immunol. 52 (3): 224-31. doi:10.1111/j.1600-0897.2004.00210.x. PMID 15373763.
Hurtado-Lorenzo A, Skinner M, El Annan J, et al. (2006). "V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway.". Nat. Cell Biol. 8 (2): 124-36. doi:10.1038/ncb1348. PMID 16415858.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635-48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Ntrivalas E, Gilman-Sachs A, Kwak-Kim J, Beaman K (2007). "The N-terminus domain of the a2 isoform of vacuolar ATPase can regulate interleukin-1beta production from mononuclear cells in co-culture with JEG-3 choriocarcinoma cells.". Am. J. Reprod. Immunol. 57 (3): 201-9. doi:10.1111/j.1600-0897.2006.00463.x. PMID 17295899.