ATOH1
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Atonal homolog 1 (Drosophila), also known as ATOH1, is a human gene.[1]
This protein belongs to the basic helix-loop-helix (BHLH) family of transcription factors. It activates E-box dependent transcription along with E47.[1]
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[edit] Further reading
- Leow CC, Polakis P, Gao WQ (2006). "A role for Hath1, a bHLH transcription factor, in colon adenocarcinoma.". Ann. N. Y. Acad. Sci. 1059: 174–83. doi: . PMID 16382053.
- Ben-Arie N, McCall AE, Berkman S, et al. (1997). "Evolutionary conservation of sequence and expression of the bHLH protein Atonal suggests a conserved role in neurogenesis.". Hum. Mol. Genet. 5 (9): 1207–16. PMID 8872459.
- Helms AW, Johnson JE (1998). "Progenitors of dorsal commissural interneurons are defined by MATH1 expression.". Development 125 (5): 919–28. PMID 9449674.
- Dintilhac A, Bernués J (2002). "HMGB1 interacts with many apparently unrelated proteins by recognizing short amino acid sequences.". J. Biol. Chem. 277 (9): 7021–8. doi: . PMID 11748221.
- Brown NL, Dagenais SL, Chen CM, Glaser T (2002). "Molecular characterization and mapping of ATOH7, a human atonal homolog with a predicted role in retinal ganglion cell development.". Mamm. Genome 13 (2): 95–101. doi: . PMID 11889557.
- Leonard JH, Cook AL, Van Gele M, et al. (2002). "Proneural and proneuroendocrine transcription factor expression in cutaneous mechanoreceptor (Merkel) cells and Merkel cell carcinoma.". Int. J. Cancer 101 (2): 103–10. doi: . PMID 12209986.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi: . PMID 12477932.
- Gazit R, Krizhanovsky V, Ben-Arie N (2004). "Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway.". Development 131 (4): 903–13. doi: . PMID 14757642.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi: . PMID 15489334.
- Sekine A, Akiyama Y, Yanagihara K, Yuasa Y (2006). "Hath1 up-regulates gastric mucin gene expression in gastric cells.". Biochem. Biophys. Res. Commun. 344 (4): 1166–71. doi: . PMID 16647036.
- Mutoh H, Sakamoto H, Hayakawa H, et al. (2006). "The intestine-specific homeobox gene Cdx2 induces expression of the basic helix-loop-helix transcription factor Math1.". Differentiation 74 (6): 313–21. doi: . PMID 16831200.
- Park ET, Oh HK, Gum JR, et al. (2006). "HATH1 expression in mucinous cancers of the colorectum and related lesions.". Clin. Cancer Res. 12 (18): 5403–10. doi: . PMID 17000673.
- Tsuchiya K, Nakamura T, Okamoto R, et al. (2007). "Reciprocal targeting of Hath1 and beta-catenin by Wnt glycogen synthase kinase 3beta in human colon cancer.". Gastroenterology 132 (1): 208–20. doi: . PMID 17241872.
- Du X, Jensen P, Goldowitz D, Hamre KM (2007). "Wild-type cells rescue genotypically Math1-null hair cells in the inner ears of chimeric mice.". Dev. Biol. 305 (2): 430–8. doi: . PMID 17397818.
- Westerman BA, Breuer RH, Poutsma A, et al. (2007). "Basic helix-loop-helix transcription factor profiling of lung tumors shows aberrant expression of the proneural gene atonal homolog 1 (ATOH1, HATH1, MATH1) in neuroendocrine tumors.". Int. J. Biol. Markers 22 (2): 114–23. PMID 17549667.
- Scheffer D, Sage C, Corey DP, Pingault V (2007). "Gene expression profiling identifies Hes6 as a transcriptional target of ATOH1 in cochlear hair cells.". FEBS Lett. 581 (24): 4651–6. doi: . PMID 17826772.
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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