Asparagusate reductase

From Wikipedia, the free encyclopedia

In enzymology, an asparagusate reductase (EC 1.8.1.11) is an enzyme that catalyzes the chemical reaction

3-mercapto-2-mercaptomethylpropanoate + NAD⁺ asparagusate + NADH + H⁺

Thus, the two substrates of this enzyme are 3-mercapto-2-mercaptomethylpropanoate and NAD⁺, whereas its 3 products are asparagusate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on a sulfur group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3-mercapto-2-mercaptomethylpropanoate:NAD+ oxidoreductase. Other names in common use include asparagusate dehydrogenase, asparagusic dehydrogenase, asparagusate reductase (NADH2), and NADH2:asparagusate oxidoreductase.

[edit] References

• IUBMB entry for 1.8.1.11
• BRENDA references for 1.8.1.11 (Recommended.)
• PubMed references for 1.8.1.11
• PubMed Central references for 1.8.1.11
• Google Scholar references for 1.8.1.11
• Yanagawa H, Egami F (1975). "Asparagusate dehydrogenases and lipoyl dehydrogenase from asparagus mitochondria". Biochim. Biophys. Acta. 384: 342–52. PMID 1125255. 
• Yanagawa H, Egami F (1976). "Asparagusate dehydrogenases and lipoyl dehydrogenase from asparagus mitochondria. Physical, chemical, and enzymatic properties". J. Biol. Chem. 251: 3637–44. PMID 180003. 

[edit] External links

The CAS registry number for this enzyme class is 56126-52-4.

• IUBMB entry for 1.8.1.11

• KEGG entry for 1.8.1.11

• BRENDA entry for 1.8.1.11

• NiceZyme view of 1.8.1.11

• EC2PDB: PDB structures for 1.8.1.11

• PRIAM entry for 1.8.1.11

• PUMA2 entry for 1.8.1.11

• IntEnz: Integrated Enzyme entry for 1.8.1.11

• MetaCyc entry for 1.8.1.11

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050445: asparagusate reductase

• AMIGO entry for GO code 0050445: asparagusate reductase