ASF1B

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ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
Identifiers
Symbol(s) ASF1B; CIA-II; FLJ10604
External IDs OMIM: 609190 MGI: 1914179 HomoloGene: 56797
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 55723 66929
Ensembl ENSG00000105011 ENSMUSG00000005470
Refseq NM_018154 (mRNA)
NP_060624 (protein)		 NM_024184 (mRNA)
NP_077146 (protein)
Location Chr 19: 14.09 - 14.11 Mb Chr 8: 86.85 - 86.86 Mb
Pubmed search [1] [2]

ASF1 anti-silencing function 1 homolog B (S. cerevisiae), also known as ASF1B, is a human gene.[1]

This gene encodes a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The encoded protein is the substrate of the tousled-like kinase family of cell cycle-regulated kinases, and may play a key role in modulating the nucleosome structure of chromatin by ensuring a constant supply of histones at sites of nucleosome assembly.[1]

[edit] References

  1. ^ a b Entrez Gene: ASF1B ASF1 anti-silencing function 1 homolog B (S. cerevisiae).

[edit] Further reading

  • Loyola A, Almouzni G (2004). "Histone chaperones, a supporting role in the limelight.". Biochim. Biophys. Acta 1677 (1-3): 3–11. doi:10.1016/j.bbaexp.2003.09.012. PMID 15020040. 
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149. 
  • Silljé HH, Nigg EA (2001). "Identification of human Asf1 chromatin assembly factors as substrates of Tousled-like kinases.". Curr. Biol. 11 (13): 1068–73. PMID 11470414. 
  • Mello JA, Silljé HH, Roche DM, et al. (2002). "Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway.". EMBO Rep. 3 (4): 329–34. doi:10.1093/embo-reports/kvf068. PMID 11897662. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Umehara T, Horikoshi M (2003). "Transcription initiation factor IID-interactive histone chaperone CIA-II implicated in mammalian spermatogenesis.". J. Biol. Chem. 278 (37): 35660–7. doi:10.1074/jbc.M303549200. PMID 12842904. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197. 
  • Groth A, Ray-Gallet D, Quivy JP, et al. (2005). "Human Asf1 regulates the flow of S phase histones during replicational stress.". Mol. Cell 17 (2): 301–11. doi:10.1016/j.molcel.2004.12.018. PMID 15664198. 
  • Sen SP, De Benedetti A (2006). "TLK1B promotes repair of UV-damaged DNA through chromatin remodeling by Asf1.". BMC Mol. Biol. 7: 37. doi:10.1186/1471-2199-7-37. PMID 17054786. 
  • Hayashi R, Goto Y, Tanaka R, et al. (2007). "Transcriptional regulation of human chromatin assembly factor ASF1.". DNA Cell Biol. 26 (2): 91–9. doi:10.1089/dna.2006.0515. PMID 17328667. 
  • Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931. 
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