Aryl-alcohol dehydrogenase (NADP+)

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In enzymology, an aryl-alcohol dehydrogenase (NADP+) (EC 1.1.1.91) is an enzyme that catalyzes the chemical reaction

an aromatic alcohol + NADP⁺ an aromatic aldehyde + NADPH + H⁺

Thus, the two substrates of this enzyme are aromatic alcohol and NADP⁺, whereas its 3 products are aromatic aldehyde, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is aryl-alcohol:NADP+ oxidoreductase. Other names in common use include aryl alcohol dehydrogenase (nicotinamide adenine dinucleotide, phosphate), coniferyl alcohol dehydrogenase, NADPH-linked benzaldehyde reductase, and aryl-alcohol dehydrogenase (NADP+).

[edit] References

• IUBMB entry for 1.1.1.91
• BRENDA references for 1.1.1.91 (Recommended.)
• PubMed references for 1.1.1.91
• PubMed Central references for 1.1.1.91
• Google Scholar references for 1.1.1.91
• Gross GG, Zenk MH (1969). "[Reduction of aromatic acids to aldehydes and alcohols in the cell-free system. 2. Purification and properties of aryl-alcohol: NADP-oxidoreductase from Neurospora crassa]". Eur. J. Biochem. 8: 420–5. PMID 4389864. 

[edit] External links

The CAS registry number for this enzyme class is 37250-27-4.

• IUBMB entry for 1.1.1.91

• KEGG entry for 1.1.1.91

• BRENDA entry for 1.1.1.91

• NiceZyme view of 1.1.1.91

• EC2PDB: PDB structures for 1.1.1.91

• PRIAM entry for 1.1.1.91

• PUMA2 entry for 1.1.1.91

• IntEnz: Integrated Enzyme entry for 1.1.1.91

• MetaCyc entry for 1.1.1.91

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047681: aryl-alcohol dehydrogenase (NADP+)

• AMIGO entry for GO code 0047681: aryl-alcohol dehydrogenase (NADP+)