Talk:Arp2/3 complex

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	Arp2/3 complex has been listed as one of the Natural sciences good articles under the good article criteria. If you can improve it further, please do. If it no longer meets these criteria, you can delist it, or ask for a reassessment.
February 23, 2007 Good article nominee Listed

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Hey, I am not sure if the article is that good yet. I am planning to keep improving it though. --Splette 15:14, 27 February 2006 (UTC)

I think it should say that in the barbed-branching model arp2/3 associates with the pointed end. I couldn't access the article.

amulekii

• Hi Amulekii, no that appears to be wrong. Just as written in the article in the barbed-branching model arp2/3 associates with the barbed end. Here is a good article from Biochem J, freely accessible: Signalling to actin assembly via the WASP-family proteins and the Arp2/3 complex In the article they summarize the existing models: "Despite the popularity of the dendritic-nucleation model, data obtained by other groups have led to the development of an alternative barbed-end branching model. Pantaloni et al. proposed that activated Arp2/3 complex binds to the barbed end of the actin filament, rather than at the side, and that the rate of Arp2/3-mediated actin polymerization is proportional to the number of free barbed ends, not the total length of the actin mother filament." I hope this clears things up a bit. Thanks for contacting me on my talk page about it. --Splette ^Talk 13:14, 18 May 2006 (UTC)

Oh yeah. I got you. I should have looked more carefully at the pictures you provided. Amulekii 21:37, 18 May 2006 (UTC)

Shouldn't it say Wiskott-Aldrich Syndrome Protein family instead of Wiskott-Aldrich Syndrome family protein? Amulekii 21:43, 18 May 2006 (UTC)