ARL8A

From Wikipedia, the free encyclopedia

ADP-ribosylation factor-like 8A

PDB rendering based on 1zd9.

Available structures: 1zd9, 2al7, 2h18

Identifiers

Symbol(s)

ARL8A; ARL10B; FLJ45195; GIE2

External IDs

MGI: 1915974 HomoloGene: 23600

Gene ontology
Molecular Function:	• nucleotide binding • GTPase activity • GTP binding • alpha-tubulin binding • beta-tubulin binding
Cellular Component:	• intracellular • cytoplasm • membrane • midbody • spindle midzone
Biological Process:	• chromosome segregation • small GTPase mediated signal transduction

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_138795 (mRNA)
NP_620150 (protein)

NM_026823 (mRNA)
NP_081099 (protein)

Location

Chr 1: 200.37 - 200.38 Mb

Chr 1: 136.96 - 136.97 Mb

Pubmed search

[1]

[2]

ADP-ribosylation factor-like 8A, also known as ARL8A, is a human gene.^[1]

[edit] References

^ Entrez Gene: ARL8A ADP-ribosylation factor-like 8A.

[edit] Further reading

Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315-21. doi:10.1038/nature04727. PMID 16710414.
Hofmann I, Munro S (2006). "An N-terminally acetylated Arf-like GTPase is localised to lysosomes and affects their motility.". J. Cell. Sci. 119 (Pt 8): 1494-503. doi:10.1242/jcs.02958. PMID 16537643.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Okai T, Araki Y, Tada M, et al. (2005). "Novel small GTPase subfamily capable of associating with tubulin is required for chromosome segregation.". J. Cell. Sci. 117 (Pt 20): 4705-15. doi:10.1242/jcs.01347. PMID 15331635.
Secombe J, Parkhurst SM (2004). "Drosophila Topors is a RING finger-containing protein that functions as a ubiquitin-protein isopeptide ligase for the hairy basic helix-loop-helix repressor protein.". J. Biol. Chem. 279 (17): 17126-33. doi:10.1074/jbc.M310097200. PMID 14871887.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791-806. PMID 8889548.