Talk:Aripiprazole
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[edit] EPS
Why isn't there any mention of it's potential for extrapyramidal side effects
[edit] Effects
Surely weight gain is a side effect as with other atyp anti psy.??? 220.237.158.214 10:22, 26 September 2007 (UTC)
Can anyone find specific information about what this medication does?
What specific kind of information are you looking for?
Search Google for aripiprazole and you will find more information than you may wish to digest.
This is just medical justifiation of many cases of mind control
Yes, I need this class of drug. Thanks for the info - I am going on a drug trial of this.
The statement that there are case reports of abilify inducing mania needs citations. Medline does not show any such case reports in my search, and I have never heard this. Abilify is used to treat mania. It can cause akathesia and states of agitation, which are not the same as mania, although may be confused with mania. It does not cause weight gain, unlike most of the other atypical agents. —Preceding unsigned comment added by Lizdoc (talk • contribs) 17:31, 14 February 2008 (UTC)
[edit] Anecdotal evidence
I know Wikipedia prohibits original research, but I know that I experienced tardive dyskinesia and insomnia after only about a week on this drug (prescribed for manic break). I was also taking an antibiotic that is metabolized by the liver, so I think that was blocking the pathway and may have strengthened the effect some. Is there any data to be had as to how common such reactions are among users of the drug, or is still too early? I was rather upset, to say the least, once I had recovered to find that I had been put on such an untried medication. Now I'm on Depakote, which seems to stabilize me without any significant side effects Evan Donovan 03:10, 25 March 2006 (UTC)
- Anti-biotics commonly interact with many drugs.J. M. 02:25, 22 May 2006 (UTC)
- What you was experiencig after a week of aripiprazole medication almost certainly was not tardive dyskinesia, unless you've been taking other antipsychotics before at least for some weeks (rather months or years); what it well could have been would be early extrapyramidal syndrome; in this cases, dystonia, dyskinesia, akathisia and the like are not uncommon. Insomnia could have been a side-effect of aripiprazole medication; and some antibiotics are certainly inhibiting microsomal metabolism of other drugs, aripiprazole included. Wish you all best with current therapy.--Spiperon 09:21, 4 May 2007 (UTC)
I would not consider this "original research" anymore maybe it is time some doc wrote an article on this so we can make it a fact. Oh i know this is not a "request page" but can someone clarify that MAJOR WARNING!!! message at the bottom of this page? its making me nervous.
I would just like to add that within one month of my starting Abilify, I started having severe restless leg syndrome. Just another side effect to look out for with this drug. —Preceding unsigned comment added by 66.140.82.161 (talk) 16:31, 28 March 2008 (UTC)
[edit] Spelling
Please correct "miscle", etc under "Side Effects"
[edit] Tardive dysphrenia
I've included a link to the new wiki Tardive dysphrenia (under See Also), which I hope, must be of interest to this one. Cheers, LFrota.
[edit] Major Warning!
Waring: This drug (even at low dosages) may cause liver failure/disease, high chlosterol, diabetes, and weight gain, etc.
This guy better be screwing around! ill rather die than to go trough this kinda fucked up stuff... oh and cholesterol is misspelled... can someone clarify this ASAP? (please?)
[edit] Not an azole
Who names these drugs? It's not an azole! Bloody pharmacologists.
-- Tom Anderson 2007-06-14 23:55 +0100
http://www.abilify.com/ lists these side effects:
"Elderly patients, diagnosed with psychosis as a result of dementia (for example, an inability to perform daily activities as a result of increased memory loss), and who are treated with atypical antipsychotic medicines including ABILIFY, are at an increased risk of death when compared to patients who are treated with a placebo (sugar pill). ABILIFY is not approved for the treatment of patients with dementia-related psychosis.
Serious side effects can occur with any antipsychotic medicine, including ABILIFY. Tell your healthcare professional right away if you have any conditions or side effects, including the following: Very high fever, rigid muscles, shaking, confusion, sweating, or increased heart rate and blood pressure. These may be signs of a condition called neuroleptic malignant syndrome (NMS), a rare but serious side effect which could be fatal
Abnormal or uncontrollable movements. These may be signs of a serious condition called tardive dyskinesia, which may be permanent Elderly: An increased risk of stroke and ministroke has been reported in a clinical study of elderly patients with dementia-related psychosis Diabetes, risk factors for diabetes (for example, obesity, family history of diabetes), or unexpected increases in thirst, urination, or hunger. Increases in blood sugar levels (hyperglycemia), in some cases serious and associated with coma or death, have been reported in patients taking medicines like ABILIFY. Ask your healthcare professional about the need to monitor your blood sugar level before and during treatment
Lightheadedness or faintness caused by a sudden change in heart rate and blood pressure when rising quickly from a sitting or lying position (orthostatic hypotension) has been reported with ABILIFY. Medicines like ABILIFY can affect your judgment, thinking, or motor skills. You should not drive or operate hazardous machinery until you know how ABILIFY affects you.
Since medicines like ABILIFY can impact your body’s ability to reduce body temperature, you should avoid overheating and dehydration.
Medicines like ABILIFY have been associated with swallowing problems (dysphagia). If you had or have swallowing problems, you should tell your healthcare professional.
If you have suicidal thoughts, you should tell your healthcare professional right away.
While taking ABILIFY, avoid: Drinking alcohol Breast-feeding an infant
Tell your healthcare professional if you have a history of seizures, or are pregnant or intend to become pregnant, and about all prescription and non-prescription medicines you are taking or plan to take.
Other common side effects include: headache, anxiety, insomnia, nausea, vomiting, constipation, dizziness, upset stomach, and an inner sense of restlessness or need to move (akathisia).
For patients who must limit their sugar intake, ABILIFY Oral Solution contains sugar.
For patients who cannot metabolize phenylalanine (those with phenylketonuria or PKU), ABILIFY® DISCMELT™ (aripiprazole) contains phenylalanine. "
-- Jend80 —Preceding unsigned comment added by 87.127.97.148 (talk) 23:39, 31 August 2007 (UTC)
[edit] New Indication for Major Depressive Disorder
On 11/16/2007, US FDA approved aripiprazole for use as adjunctive therapy for Major Depressive Disorder (unipolar depression).
For this purpose, it is usually prescribed at a much lower dose than for bipolar or schizophrenia (schiz= 10-15 mg/day, bipolar=15-30 mg/day, major depress=5-10 mg/day with starting dose of only 2 mg/day).
This is listed on FDA website:
and new FDA labeling info is here:
http://www.fda.gov/cder/foi/label/2007/021436s018,021713s013,21729s005,021866s005lbl.pdf
Crazymiddle (talk) 03:57, 22 November 2007 (UTC)
