ARHGAP24

From Wikipedia, the free encyclopedia

Rho GTPase activating protein 24

Identifiers

ARHGAP24; DKFZP564B1162; FILGAP; FLJ33877; RC-GAP72; RCGAP72; p73; p73RhoGAP

External IDs

OMIM: 610586 MGI: 1922647 HomoloGene: 32754

Gene ontology
Molecular Function:	• GTPase activator activity • protein binding
Cellular Component:	• intracellular • plasma membrane
Biological Process:	• signal transduction

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_001025616 (mRNA)
NP_001020787 (protein)

NM_029270 (mRNA)
NP_083546 (protein)

Location

Chr 4: 86.62 - 87.14 Mb

Chr 5: 102.72 - 103.14 Mb

Pubmed search

[1]

[2]

Rho GTPase activating protein 24, also known as ARHGAP24, is a human gene.^[1]

[edit] References

^ Entrez Gene: ARHGAP24 Rho GTPase activating protein 24.

[edit] Further reading

"Toward a complete human genome sequence." (1999). Genome Res. 8 (11): 1097–108. PMID 9847074.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. doi:10.1101/gr.154701. PMID 11230166.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMID 11256614.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Lee SY, Obata Y, Yoshida M, et al. (2003). "Immunomic analysis of human sarcoma.". Proc. Natl. Acad. Sci. U.S.A. 100 (5): 2651–6. doi:10.1073/pnas.0437972100. PMID 12601173.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Katoh M, Katoh M (2005). "Identification and characterization of ARHGAP24 and ARHGAP25 genes in silico.". Int. J. Mol. Med. 14 (2): 333–8. PMID 15254788.
Su ZJ, Hahn CN, Goodall GJ, et al. (2004). "A vascular cell-restricted RhoGAP, p73RhoGAP, is a key regulator of angiogenesis.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12212–7. doi:10.1073/pnas.0404631101. PMID 15302923.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Lavelin I, Geiger B (2005). "Characterization of a novel GTPase-activating protein associated with focal adhesions and the actin cytoskeleton.". J. Biol. Chem. 280 (8): 7178–85. doi:10.1074/jbc.M411990200. PMID 15611138.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.
Ohta Y, Hartwig JH, Stossel TP (2006). "FilGAP, a Rho- and ROCK-regulated GAP for Rac binds filamin A to control actin remodelling.". Nat. Cell Biol. 8 (8): 803–14. doi:10.1038/ncb1437. PMID 16862148.