ARC Weekly Top 40 number-one hits of 2000 (U.S.)
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These are the ARC Weekly Top 40 number one hits of 2000.
| Issue Date | Song | Artist |
| January 1 | I Wanna Love You Forever | Jessica Simpson |
| January 8 | I Wanna Love You Forever | Jessica Simpson |
| January 15 | What a Girl Wants | Christina Aguilera |
| January 22 | What a Girl Wants | Christina Aguilera |
| January 29 | What a Girl Wants | Christina Aguilera |
| February 5 | Show Me the Meaning of Being Lonely | Backstreet Boys |
| February 12 | Show Me the Meaning of Being Lonely | Backstreet Boys |
| February 19 | Show Me the Meaning of Being Lonely | Backstreet Boys |
| February 26 | Show Me the Meaning of Being Lonely | Backstreet Boys |
| March 4 | Bye Bye Bye | *NSYNC |
| March 11 | Bye Bye Bye | *NSYNC |
| March 18 | Bye Bye Bye | *NSYNC |
| March 25 | Bye Bye Bye | *NSYNC |
| April 1 | Bye Bye Bye | *NSYNC |
| April 8 | Bye Bye Bye | *NSYNC |
| April 15 | Bye Bye Bye | *NSYNC |
| April 22 | Bye Bye Bye | *NSYNC |
| April 29 | Bye Bye Bye | *NSYNC |
| May 6 | Say My Name | Destiny's Child |
| May 13 | I Try | Macy Gray |
| May 20 | Oops!...I Did It Again | Britney Spears |
| May 27 | Oops!...I Did It Again | Britney Spears |
| June 3 | Oops!...I Did It Again | Britney Spears |
| June 10 | Oops!...I Did It Again | Britney Spears |
| June 17 | Oops!...I Did It Again | Britney Spears |
| June 24 | Oops!...I Did It Again | Britney Spears |
| July 1 | It's Gonna Be Me | *NSYNC |
| July 8 | It's Gonna Be Me | *NSYNC |
| July 15 | It's Gonna Be Me | *NSYNC |
| July 22 | It's Gonna Be Me | *NSYNC |
| July 29 | It's Gonna Be Me | *NSYNC |
| August 5 | It's Gonna Be Me | *NSYNC |
| August 12 | Bent | matchbox twenty |
| August 19 | Bent | matchbox twenty |
| August 26 | Bent | matchbox twenty |
| September 2 | Doesn't Really Matter | Janet |
| September 9 | Jumpin', Jumpin' | Destiny's Child |
| September 16 | Music | Madonna |
| September 23 | Music | Madonna |
| September 30 | Music | Madonna |
| October 7 | Kryptonite | 3 Doors Down |
| October 14 | Kryptonite | 3 Doors Down |
| October 21 | Kryptonite | 3 Doors Down |
| October 28 | Come on Over Baby (All I Want Is You) | Christina Aguilera |
| November 4 | With Arms Wide Open | Creed |
| November 11 | With Arms Wide Open | Creed |
| November 18 | With Arms Wide Open | Creed |
| November 25 | With Arms Wide Open | Creed |
| December 2 | With Arms Wide Open | Creed |
| December 9 | Independent Women Part 1 | Destiny's Child |
| December 16 | Independent Women Part 1 | Destiny's Child |
| December 23 | Independent Women Part 1 | Destiny's Child |
| December 30 | Independent Women Part 1 | Destiny's Child |
