AQP8

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Aquaporin 8
Identifiers
Symbol(s) AQP8;
External IDs OMIM: 603750 MGI: 1195271 HomoloGene: 68166
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 343 11833
Ensembl ENSG00000103375 ENSMUSG00000030762
Uniprot O94778 P56404
Refseq NM_001169 (mRNA)
NP_001160 (protein)		 NM_007474 (mRNA)
NP_031500 (protein)
Location Chr 16: 25.14 - 25.15 Mb Chr 7: 123.25 - 123.26 Mb
Pubmed search [1] [2]

Aquaporin 8, also known as AQP8, is a human gene.[1]

Aquaporin 8 (AQP8) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 8 mRNA is found in pancreas and colon but not other tissues.[1]

Contents

[edit] See also

[edit] References

  1. ^ a b Entrez Gene: AQP8 aquaporin 8.

[edit] Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298. 
  • Harrington DJ, Adachi K, Royer WE (1997). "The high resolution crystal structure of deoxyhemoglobin S.". J. Mol. Biol. 272 (3): 398–407. doi:10.1006/jmbi.1997.1253. PMID 9325099. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149. 
  • Koyama N, Ishibashi K, Kuwahara M, et al. (1999). "Cloning and functional expression of human aquaporin8 cDNA and analysis of its gene.". Genomics 54 (1): 169–72. doi:10.1006/geno.1998.5552. PMID 9806845. 
  • Viggiano L, Rocchi M, Svelto M, Calamita G (1999). "Assignment of the aquaporin-8 water channel gene (AQP8) to human chromosome 16p12.". Cytogenet. Cell Genet. 84 (3-4): 208–10. PMID 10393433. 
  • Fischer H, Stenling R, Rubio C, Lindblom A (2003). "Differential expression of aquaporin 8 in human colonic epithelial cells and colorectal tumors.". BMC Physiol. 1: 1. PMID 11231887. 
  • Harrington JJ, Sherf B, Rundlett S, et al. (2001). "Creation of genome-wide protein expression libraries using random activation of gene expression.". Nat. Biotechnol. 19 (5): 440–5. doi:10.1038/88107. PMID 11329013. 
  • Wang S, Kallichanda N, Song W, et al. (2001). "Expression of aquaporin-8 in human placenta and chorioamniotic membranes: evidence of molecular mechanism for intramembranous amniotic fluid resorption.". Am. J. Obstet. Gynecol. 185 (5): 1226–31. doi:10.1067/mob.2001.117971. PMID 11717661. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Wang S, Chen J, Au KT, Ross MG (2003). "Expression of aquaporin 8 and its up-regulation by cyclic adenosine monophosphate in human WISH cells.". Am. J. Obstet. Gynecol. 188 (4): 997–1001. PMID 12712100. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Zahn A, Moehle C, Langmann T, et al. (2007). "Aquaporin-8 expression is reduced in ileum and induced in colon of patients with ulcerative colitis.". World J. Gastroenterol. 13 (11): 1687–95. PMID 17461471. 

[edit] External links

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Membrane transport protein: ion channels
Ca2+: Calcium channel
Na+: Sodium channel
Navα (1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.9, 7A) • Navβ (1, 2, 3, 4) • Epithelial sodium channel
K+: Potassium channel
Cl-: Chloride channel
Porin
Cations: TRP
TRPA (1) • TRPC (1, 2, 3, 4, 4AP, 5, 6, 7) • TRPM (1, 2, 3, 4, 5, 6, 7, 8) • TRPML (Mucolipin-1) • TRPP (1, 2) • TRPV (1, 2, 3, 4, 5, 6)
Other/general