Aprobarbital
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Aprobarbital
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Systematic (IUPAC) name | |
5-propan-2-yl-5-prop-2-enyl-1,3-diazinane-2,4,6-trione | |
Identifiers | |
CAS number | |
ATC code | N05 |
PubChem | |
Chemical data | |
Formula | C10H14N2O3 |
Mol. mass | 210.23 g/mol |
Synonyms | Aprobarbital, Oramon, Allylpropymal, Alurate, 5-Isopropyl-5-allylbarbituric acid |
Pharmacokinetic data | |
Bioavailability | ? |
Metabolism | ? |
Half life | ? |
Excretion | ? |
Therapeutic considerations | |
Pregnancy cat. |
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Legal status | |
Routes | ? |
Aprobarbital (Oramon) is a barbiturate derivative invented in the 1920s by Ernst Preiswerk. It has sedative, hypnotic and anticonvulsant properties, and was used primarily for the treatment of insomnia. [1] Aprobarbital was never as widely used as more common barbiturate derivatives such as phenobarbital and is now rarely prescribed as it has been replaced by newer drugs with a better safety margin.
[edit] References
- ^ Reddemann H, Turk E. Oramon poisoning in infancy and childhood. Observations on 12 aprobarbital poisonings (German). Das Deutsche Gesundheitswesen. 1966 May 12;21(19):878-81.
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