APOL6

From Wikipedia, the free encyclopedia

Apolipoprotein L, 6

Identifiers

APOL6; APOL-VI; DKFZp667M075; FLJ38562; FLJ90164; MGC57495

External IDs

OMIM: 607256 MGI: 1919189 HomoloGene: 49940

Gene ontology
Molecular Function:	• lipid transporter activity • lipid binding
Cellular Component:	• extracellular region • cytoplasm
Biological Process:	• lipid transport • lipoprotein metabolic process

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

Refseq

NM_030641 (mRNA)
NP_085144 (protein)

XM_001000453 (mRNA)
XP_001000453 (protein)

Location

Chr 22: 34.37 - 34.39 Mb

Chr 15: 76.87 - 76.88 Mb

Pubmed search

[1]

[2]

Apolipoprotein L, 6, also known as APOL6, is a human gene.^[1]

This gene is a member of the apolipoprotein L gene family. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids or allow the binding of lipids to organelles.^[1]

[edit] References

^ ^a ^b Entrez Gene: APOL6 apolipoprotein L, 6.

[edit] Further reading

Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791–806. PMID 8889548.
Dominguez O, Ashhab Y, Sabater L, et al. (1999). "Cloning of ARE-containing genes by AU-motif-directed display.". Genomics 54 (2): 278–86. doi:10.1006/geno.1998.5548. PMID 9828130.
Dunham I, Shimizu N, Roe BA, et al. (1999). "The DNA sequence of human chromosome 22.". Nature 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208.
Page NM, Butlin DJ, Lomthaisong K, Lowry PJ (2001). "The human apolipoprotein L gene cluster: identification, classification, and sites of distribution.". Genomics 74 (1): 71–8. doi:10.1006/geno.2001.6534. PMID 11374903.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMID 12975309.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Collins JE, Wright CL, Edwards CA, et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome.". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMID 15461802.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Liu Z, Lu H, Jiang Z, et al. (2005). "Apolipoprotein l6, a novel proapoptotic Bcl-2 homology 3-only protein, induces mitochondria-mediated apoptosis in cancer cells.". Mol. Cancer Res. 3 (1): 21–31. PMID 15671246.