AP3S1

From Wikipedia, the free encyclopedia

Adaptor-related protein complex 3, sigma 1 subunit

Identifiers

AP3S1; CLAPS3; Sigma3A

External IDs

OMIM: 601507 MGI: 1337062 HomoloGene: 4254

Gene ontology
Molecular Function:	• transporter activity
Cellular Component:	• AP-type membrane coat adaptor complex • transport vesicle • coated vesicle membrane
Biological Process:	• transport • intracellular protein transport • insulin receptor signaling pathway

Orthologs

Human

Mouse

n/a

n/a

Refseq

NM_001002924 (mRNA)
NP_001002924 (protein)

NM_009681 (mRNA)
NP_033811 (protein)

Location

n/a

Chr 18: 46.87 - 46.92 Mb

Pubmed search

[1]

[2]

Adaptor-related protein complex 3, sigma 1 subunit, also known as AP3S1, is a human gene.^[1]

[edit] References

^ Entrez Gene: AP3S1 adaptor-related protein complex 3, sigma 1 subunit.

[edit] Further reading

Watanabe TK, Shimizu F, Nagata M, et al. (1996). "Cloning, expression pattern and mapping to 12p 13.2 --> p13.1 of CLAPS3, a gene encoding a novel clathrin-adaptor small chain.". Cytogenet. Cell Genet. 73 (3): 214-7. PMID 8697810.
Dell'Angelica EC, Ohno H, Ooi CE, et al. (1997). "AP-3: an adaptor-like protein complex with ubiquitous expression.". EMBO J. 16 (5): 917-28. doi:10.1093/emboj/16.5.917. PMID 9118953.
Simpson F, Peden AA, Christopoulou L, Robinson MS (1997). "Characterization of the adaptor-related protein complex, AP-3.". J. Cell Biol. 137 (4): 835-45. PMID 9151686.
VanRenterghem B, Morin M, Czech MP, Heller-Harrison RA (1998). "Interaction of insulin receptor substrate-1 with the sigma3A subunit of the adaptor protein complex-3 in cultured adipocytes.". J. Biol. Chem. 273 (45): 29942-9. PMID 9792713.
Rodionov DG, Höning S, Silye A, et al. (2003). "Structural requirements for interactions between leucine-sorting signals and clathrin-associated adaptor protein complex AP3.". J. Biol. Chem. 277 (49): 47436-43. doi:10.1074/jbc.M207149200. PMID 12370188.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Nie Z, Boehm M, Boja ES, et al. (2003). "Specific regulation of the adaptor protein complex AP-3 by the Arf GAP AGAP1.". Dev. Cell 5 (3): 513-21. PMID 12967569.
Salazar G, Love R, Werner E, et al. (2004). "The zinc transporter ZnT3 interacts with AP-3 and it is preferentially targeted to a distinct synaptic vesicle subpopulation.". Mol. Biol. Cell 15 (2): 575-87. doi:10.1091/mbc.E03-06-0401. PMID 14657250.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Lefrançois S, Janvier K, Boehm M, et al. (2004). "An ear-core interaction regulates the recruitment of the AP-3 complex to membranes.". Dev. Cell 7 (4): 619-25. doi:10.1016/j.devcel.2004.08.009. PMID 15469849.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.