ANXA13

From Wikipedia, the free encyclopedia

Annexin A13

Identifiers

ANXA13; ANX13; ISA; MGC150460

External IDs

OMIM: 602573 MGI: 1917037 HomoloGene: 20908

Gene ontology
Molecular Function:	• calcium ion binding • calcium-dependent phospholipid binding
Cellular Component:	• plasma membrane
Biological Process:	• cell differentiation

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

n/a

Refseq

NM_001003954 (mRNA)
NP_001003954 (protein)

NM_027211 (mRNA)
NP_081487 (protein)

Location

Chr 8: 124.76 - 124.82 Mb

n/a

Pubmed search

[1]

[2]

Annexin A13, also known as ANXA13, is a human gene.^[1]

This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. The specific function of this gene has not yet been determined; however, it is associated with the plasma membrane of undifferentiated, proliferating endothelial cells and differentiated villus enterocytes. Alternatively spliced transcript variants encoding different isoforms have been identified.^[1]

[edit] References

^ ^a ^b Entrez Gene: ANXA13 annexin A13.

[edit] Further reading

Wice BM, Gordon JI (1992). "A strategy for isolation of cDNAs encoding proteins affecting human intestinal epithelial cell growth and differentiation: characterization of a novel gut-specific N-myristoylated annexin.". J. Cell Biol. 116 (2): 405-22. PMID 1530946.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171-4. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149-56. PMID 9373149.
Morgan RO, Bell DW, Testa JR, Fernandez MP (1998). "Genomic locations of ANX11 and ANX13 and the evolutionary genetics of human annexins.". Genomics 48 (1): 100-10. doi:10.1006/geno.1997.5148. PMID 9503022.
Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491-6. PMID 10737800.
Plant PJ, Lafont F, Lecat S, et al. (2000). "Apical membrane targeting of Nedd4 is mediated by an association of its C2 domain with annexin XIIIb.". J. Cell Biol. 149 (7): 1473-84. PMID 10871286.
Noda Y, Okada Y, Saito N, et al. (2001). "KIFC3, a microtubule minus end-directed motor for the apical transport of annexin XIIIb-associated Triton-insoluble membranes.". J. Cell Biol. 155 (1): 77-88. doi:10.1083/jcb.200108042. PMID 11581287.
Iglesias JM, Morgan RO, Jenkins NA, et al. (2002). "Comparative genetics and evolution of annexin A13 as the founder gene of vertebrate annexins.". Mol. Biol. Evol. 19 (5): 608-18. PMID 11961095.
Anderson NL, Polanski M, Pieper R, et al. (2004). "The human plasma proteome: a nonredundant list developed by combination of four separate sources.". Mol. Cell Proteomics 3 (4): 311-26. doi:10.1074/mcp.M300127-MCP200. PMID 14718574.