ANXA11

From Wikipedia, the free encyclopedia

Annexin A11

Identifiers

ANXA11; ANX11; CAP50

External IDs

OMIM: 602572 MGI: 108481 HomoloGene: 22759

Gene ontology
Molecular Function:	• calcium ion binding • protein binding • calcium-dependent phospholipid binding • phosphatidylethanolamine binding
Cellular Component:	• nucleus • nuclear envelope • nucleoplasm • cytoplasm
Biological Process:	• immune response

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_001157 (mRNA)
NP_001148 (protein)

XM_981824 (mRNA)
XP_986918 (protein)

Location

Chr 10: 81.9 - 81.96 Mb

Chr 14: 24.68 - 24.72 Mb

Pubmed search

[1]

[2]

Annexin A11, also known as ANXA11, is a human gene.^[1]

This gene encodes a member of the annexin family, a group of calcium-dependent phospholipid-binding proteins. Annexins have unique N-terminal domains and conserved C-terminal domains, which contain the calcium-dependent phospholipid-binding sites. The encoded protein is a 56-kD antigen recognized by sera from patients with various autoimmune diseases. Transcript variants encoding the same isoform have been identified.^[1]

[edit] References

^ ^a ^b Entrez Gene: ANXA11 annexin A11.

[edit] Further reading

Minami H, Tokumitsu H, Mizutani A, et al. (1993). "Specific binding of CAP-50 to calcyclin.". FEBS Lett. 305 (3): 217-9. PMID 1299619.
Dawson SJ, White LA (1992). "Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin.". J. Infect. 24 (3): 317-20. PMID 1602151.
Misaki Y, Pruijn GJ, van der Kemp AW, van Venrooij WJ (1994). "The 56K autoantigen is identical to human annexin XI.". J. Biol. Chem. 269 (6): 4240-6. PMID 7508441.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171-4. PMID 8125298.
Sjölin C, Dahlgren C (1996). "Isolation by calcium-dependent translation to neutrophil-specific granules of a 42-kD cytosolic protein, identified as being a fragment of annexin XI.". Blood 87 (11): 4817-23. PMID 8639854.
Brownawell AM, Creutz CE (1997). "Calcium-dependent binding of sorcin to the N-terminal domain of synexin (annexin VII).". J. Biol. Chem. 272 (35): 22182-90. PMID 9268363.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149-56. PMID 9373149.
Morgan RO, Bell DW, Testa JR, Fernandez MP (1998). "Genomic locations of ANX11 and ANX13 and the evolutionary genetics of human annexins.". Genomics 48 (1): 100-10. doi:10.1006/geno.1997.5148. PMID 9503022.
Sudo T, Hidaka H (1999). "Characterization of the calcyclin (S100A6) binding site of annexin XI-A by site-directed mutagenesis.". FEBS Lett. 444 (1): 11-4. PMID 10037139.
Bances P, Fernandez MR, Rodriguez-Garcia MI, et al. (2001). "Annexin A11 (ANXA11) gene structure as the progenitor of paralogous annexins and source of orthologous cDNA isoforms.". Genomics 69 (1): 95-103. doi:10.1006/geno.2000.6309. PMID 11013079.
Satoh H, Shibata H, Nakano Y, et al. (2002). "ALG-2 interacts with the amino-terminal domain of annexin XI in a Ca(2+)-dependent manner.". Biochem. Biophys. Res. Commun. 291 (5): 1166-72. doi:10.1006/bbrc.2002.6600. PMID 11883939.
Satoh H, Nakano Y, Shibata H, Maki M (2002). "The penta-EF-hand domain of ALG-2 interacts with amino-terminal domains of both annexin VII and annexin XI in a Ca2+-dependent manner.". Biochim. Biophys. Acta 1600 (1-2): 61-7. PMID 12445460.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Breen EC, Tang K (2003). "Calcyclin (S100A6) regulates pulmonary fibroblast proliferation, morphology, and cytoskeletal organization in vitro.". J. Cell. Biochem. 88 (4): 848-54. doi:10.1002/jcb.10398. PMID 12577318.
Tomas A, Moss SE (2003). "Calcium- and cell cycle-dependent association of annexin 11 with the nuclear envelope.". J. Biol. Chem. 278 (22): 20210-6. doi:10.1074/jbc.M212669200. PMID 12601007.
Farnaes L, Ditzel HJ (2003). "Dissecting the cellular functions of annexin XI using recombinant human annexin XI-specific autoantibodies cloned by phage display.". J. Biol. Chem. 278 (35): 33120-6. doi:10.1074/jbc.M210852200. PMID 12805373.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Tomas A, Futter C, Moss SE (2004). "Annexin 11 is required for midbody formation and completion of the terminal phase of cytokinesis.". J. Cell Biol. 165 (6): 813-22. doi:10.1083/jcb.200311054. PMID 15197175.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514.