Anthra(1,9-cd)pyrazol-6(2H)-one
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- The correct title of this article is Anthra[1,9-cd]pyrazol-6(2H)-one. The substitution or omission of any < > [ ] { } is due to technical restrictions.
Anthra[1,9-cd]pyrazol-6(2H)-one is chemical compound.
- anticancer agent
- selective c-Jun N-terminal protein kinase (JNK) inhibitor
[edit] References
- Showalter HD, Johnson JL, Werbel LM, Leopold WR, Jackson RC, Elslager EF (1984). "5-[(Aminoalkyl)amino]-substituted anthra[1,9-cd]pyrazol-6(2H)-ones as novel anticancer agents. Synthesis and biological evaluation". J. Med. Chem. 27 (3): 253–5. PMID 6699870.
- Okuno S, Saito A, Hayashi T, Chan PH (2004). "The c-Jun N-terminal protein kinase signaling pathway mediates Bax activation and subsequent neuronal apoptosis through interaction with Bim after transient focal cerebral ischemia". J. Neurosci. 24 (36): 7879–87. doi:. PMID 15356200.
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