Anthocyanidin reductase

From Wikipedia, the free encyclopedia

In enzymology, an anthocyanidin reductase (EC 1.3.1.77) is an enzyme that catalyzes the chemical reaction

a flavan-3-ol + 2 NAD(P)+ an anthocyanidin + 2 NAD(P)H + H⁺

The 3 substrates of this enzyme are flavan-3-ol, NAD⁺, and NADP⁺, whereas its 4 products are anthocyanidin, NADH, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is flavan-3-ol:NAD(P)+ oxidoreductase. Other names in common use include AtANR, and MtANR. This enzyme participates in flavonoid biosynthesis.

[edit] References

• IUBMB entry for 1.3.1.77
• BRENDA references for 1.3.1.77 (Recommended.)
• PubMed references for 1.3.1.77
• PubMed Central references for 1.3.1.77
• Google Scholar references for 1.3.1.77
• Xie DY, Sharma SB, Paiva NL, Ferreira D, Dixon RA (2003). "Role of anthocyanidin reductase, encoded by BANYULS in plant flavonoid biosynthesis". Science. 299: 396–9. doi:10.1126/science.1078540. PMID 12532018. 
• Xie DY, Sharma SB, Dixon RA (2004). "Anthocyanidin reductases from Medicago truncatula and Arabidopsis thaliana". Arch. Biochem. Biophys. 422: 91–102. doi:10.1016/j.abb.2003.12.011. PMID 14725861. 

[edit] External links

The CAS registry number for this enzyme class is 93389-48-1.

• IUBMB entry for 1.3.1.77

• KEGG entry for 1.3.1.77

• BRENDA entry for 1.3.1.77

• NiceZyme view of 1.3.1.77

• EC2PDB: PDB structures for 1.3.1.77

• PRIAM entry for 1.3.1.77

• PUMA2 entry for 1.3.1.77

• IntEnz: Integrated Enzyme entry for 1.3.1.77

• MetaCyc entry for 1.3.1.77

• Atomic-resolution structures of enzymes belonging to this class