ANKRD2

From Wikipedia, the free encyclopedia

Ankyrin repeat domain 2 (stretch responsive muscle)

Identifiers

ANKRD2; ARPP; MGC104314

External IDs

OMIM: 610734 MGI: 1861447 HomoloGene: 10568

Gene ontology
Molecular Function:	• structural constituent of muscle
Cellular Component:	• nucleus • sarcomere
Biological Process:	• muscle development

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_020349 (mRNA)
NP_065082 (protein)

NM_020033 (mRNA)
NP_064417 (protein)

Location

Chr 10: 99.32 - 99.33 Mb

Chr 19: 42.09 - 42.1 Mb

Pubmed search

[1]

[2]

Ankyrin repeat domain 2 (stretch responsive muscle), also known as ANKRD2, is a human gene.^[1]

[edit] References

^ Entrez Gene: ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle).

[edit] Further reading

Sosovec V, Ivicic L, Gaspar I, L'Achová B (1976). "[Incidence of benign conjugated hyperbilirubinemia with pigment in the liver in Spis (Dubin-Johnson syndrome) II. Attempts at screening of carrier state by means of BSP test]". Ceskoslovenská gastroenterologie a výz̆iva 29 (8): 517–26. PMID 1204005.
Kemp TJ, Sadusky TJ, Saltisi F, et al. (2000). "Identification of Ankrd2, a novel skeletal muscle gene coding for a stretch-responsive ankyrin-repeat protein.". Genomics 66 (3): 229–41. doi:10.1006/geno.2000.6213. PMID 10873377.
Pallavicini A, Kojić S, Bean C, et al. (2001). "Characterization of human skeletal muscle Ankrd2.". Biochem. Biophys. Res. Commun. 285 (2): 378–86. doi:10.1006/bbrc.2001.5131. PMID 11444853.
Moriyama M, Tsukamoto Y, Fujiwara M, et al. (2001). "Identification of a novel human ankyrin-repeated protein homologous to CARP.". Biochem. Biophys. Res. Commun. 285 (3): 715–23. doi:10.1006/bbrc.2001.5216. PMID 11453652.
Laveder P, De Pittà C, Toppo S, et al. (2002). "A two-step strategy for constructing specifically self-subtracted cDNA libraries.". Nucleic Acids Res. 30 (9): e38. PMID 11972353.
Tsukamoto Y, Senda T, Nakano T, et al. (2002). "Arpp, a new homolog of carp, is preferentially expressed in type 1 skeletal muscle fibers and is markedly induced by denervation.". Lab. Invest. 82 (5): 645–55. PMID 12004005.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Nakamura K, Nakada C, Takeuchi K, et al. (2003). "Altered expression of cardiac ankyrin repeat protein and its homologue, ankyrin repeat protein with PEST and proline-rich region, in atrophic muscles in amyotrophic lateral sclerosis.". Pathobiology 70 (4): 197–203. doi:10.1159/000069329. PMID 12679596.
Miller MK, Bang ML, Witt CC, et al. (2003). "The muscle ankyrin repeat proteins: CARP, ankrd2/Arpp and DARP as a family of titin filament-based stress response molecules.". J. Mol. Biol. 333 (5): 951–64. PMID 14583192.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Kojic S, Medeot E, Guccione E, et al. (2004). "The Ankrd2 protein, a link between the sarcomere and the nucleus in skeletal muscle.". J. Mol. Biol. 339 (2): 313–25. doi:10.1016/j.jmb.2004.03.071. PMID 15136035.
Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10.". Nature 429 (6990): 375–81. doi:10.1038/nature02462. PMID 15164054.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Mckoy G, Hou Y, Yang SY, et al. (2005). "Expression of Ankrd2 in fast and slow muscles and its response to stretch are consistent with a role in slow muscle function.". J. Appl. Physiol. 98 (6): 2337–43; discussion 2320. doi:10.1152/japplphysiol.01046.2004. PMID 15677738.
Ishiguro N, Motoi T, Osaki M, et al. (2005). "Immunohistochemical analysis of a muscle ankyrin-repeat protein, Arpp, in paraffin-embedded tumors: evaluation of Arpp as a tumor marker for rhabdomyosarcoma.". Hum. Pathol. 36 (6): 620–5. doi:10.1016/j.humpath.2005.04.014. PMID 16021567.
Shomori K, Nagashima Y, Kuroda N, et al. (2007). "ARPP protein is selectively expressed in renal oncocytoma, but rarely in renal cell carcinomas.". Mod. Pathol. 20 (2): 199–207. doi:10.1038/modpathol.3800730. PMID 17206105.