Anhydrosialidase

From Wikipedia, the free encyclopedia

In enzymology, an anhydrosialidase (EC 4.2.2.15) is an enzyme that catalyzes the chemical reaction

Elimination of alpha-sialyl groups in N-acetylneuraminic acid glycosides, releasing 2,7-anhydro-alpha-N-acetylneuraminate

This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. The systematic name of this enzyme class is glycoconjugate sialyl-lyase (2,7-cyclizing). Other names in common use include anhydroneuraminidase, sialglycoconjugate N-acylneuraminylhydrolase (2,7-cyclizing), and sialidase L.

[edit] References

• IUBMB entry for 4.2.2.15
• BRENDA references for 4.2.2.15 (Recommended.)
• PubMed references for 4.2.2.15
• PubMed Central references for 4.2.2.15
• Google Scholar references for 4.2.2.15
• Li YT, Nakagawa H, Ross SA, Hansson GC, Li SC (1990). "A novel sialidase which releases 2,7-anhydro-alpha-N-acetylneuraminic acid from sialoglycoconjugates". J. Biol. Chem. 265: 21629–33. PMID 2254319. 

[edit] External links

The CAS registry number for this enzyme class is 157857-11-9.

• IUBMB entry for 4.2.2.15

• KEGG entry for 4.2.2.15

• BRENDA entry for 4.2.2.15

• NiceZyme view of 4.2.2.15

• EC2PDB: PDB structures for 4.2.2.15

• PRIAM entry for 4.2.2.15

• PUMA2 entry for 4.2.2.15

• IntEnz: Integrated Enzyme entry for 4.2.2.15

• MetaCyc entry for 4.2.2.15

• Atomic-resolution structures of enzymes belonging to this class