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[edit] Distal tubules???
I'm pretty sure amiloride works on the collecting tubule, not on the distal tubule. I'll check on this and make corrections if I'm right. —Preceding unsigned comment added by 201.130.132.118 (talk) 03:52, 26 March 2008 (UTC)
It woks on both segments, although most importantly in the principal cells of the collecting tubule, same as aldosterone.Lui1014 (talk) 04:40, 26 March 2008 (UTC)