Aminoimidazolase

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In enzymology, an aminoimidazolase (EC 3.5.4.8) is an enzyme that catalyzes the chemical reaction

4-aminoimidazole + H₂O unidentified product + NH₃

Thus, the two substrates of this enzyme are 4-aminoimidazole and H₂O, whereas its two products are unidentified product and NH₃.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. The systematic name of this enzyme class is 4-aminoimidazole aminohydrolase. This enzyme is also called 4-aminoimidazole hydrolase. This enzyme participates in purine metabolism. It employs one cofactor, iron.

[edit] References

• IUBMB entry for 3.5.4.8
• BRENDA references for 3.5.4.8 (Recommended.)
• PubMed references for 3.5.4.8
• PubMed Central references for 3.5.4.8
• Google Scholar references for 3.5.4.8
• Rabinowitz JC and Pricer WE (1956). "Purine fermentation by Clostridium cylindrosporum. V Formiminoglycine". J. Biol. Chem. 222: 537–554. 

[edit] External links

The CAS registry number for this enzyme class is 9025-17-6.

• IUBMB entry for 3.5.4.8

• KEGG entry for 3.5.4.8

• BRENDA entry for 3.5.4.8

• NiceZyme view of 3.5.4.8

• EC2PDB: PDB structures for 3.5.4.8

• PRIAM entry for 3.5.4.8

• PUMA2 entry for 3.5.4.8

• IntEnz: Integrated Enzyme entry for 3.5.4.8

• MetaCyc entry for 3.5.4.8

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047664: aminoimidazolase

• AMIGO entry for GO code 0047664: aminoimidazolase