Altronate dehydratase

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In enzymology, an altronate dehydratase (EC 4.2.1.7) is an enzyme that catalyzes the chemical reaction

D-altronate 2-dehydro-3-deoxy-D-gluconate + H₂O

Hence, this enzyme has one substrate, D-altronate, and two products, 2-dehydro-3-deoxy-D-gluconate and H₂O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is D-altronate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming). This enzyme is also called D-altronate hydro-lyase. This enzyme participates in pentose and glucuronate interconversions.

[edit] References

• IUBMB entry for 4.2.1.7
• BRENDA references for 4.2.1.7 (Recommended.)
• PubMed references for 4.2.1.7
• PubMed Central references for 4.2.1.7
• Google Scholar references for 4.2.1.7
• SMILEY JD, ASHWELL G (1960). "Uronic acid metabolism in bacteria. III. Purification and properties of D-altronic acid and D-mannonic acid dehydrases in Escherichia coli". J. Biol. Chem. 235: 1571–5. PMID 13831814. 

[edit] External links

The CAS registry number for this enzyme class is 62213-26-7.

• IUBMB entry for 4.2.1.7

• KEGG entry for 4.2.1.7

• BRENDA entry for 4.2.1.7

• NiceZyme view of 4.2.1.7

• EC2PDB: PDB structures for 4.2.1.7

• PRIAM entry for 4.2.1.7

• PUMA2 entry for 4.2.1.7

• IntEnz: Integrated Enzyme entry for 4.2.1.7

• MetaCyc entry for 4.2.1.7

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0008789: altronate dehydratase

• AMIGO entry for GO code 0008789: altronate dehydratase