Talk:Alpha-Methyltryptamine

From Wikipedia, the free encyclopedia

This article is within the scope of the following WikiProjects:

WikiProject Pharmacology (Rated start-Class) Alpha-Methyltryptamine is part of WikiProject Pharmacology, a project to improve all Pharmacology-related articles. If you would like to help improve this and other pharmacology articles, please join the project. All interested editors are welcome. Start This article has been rated as start-Class on the quality scale. Mid This article has been rated as mid-importance for this Project's importance scale. WikiProject Psychedelics, Dissociatives and Deliriants (Rated Start-Class) This article is part of WikiProject Psychedelics, Dissociatives and Deliriants, an attempt to improve Wikipedia's coverage of hallucinogens. Feel free to participate by editing this article or by visiting the project page, where you can join the project and/or contribute to the discussion. Start This article has been rated as Start-Class on the quality scale.

---

The duration of freebase alphamethyltryptamine is 10-12 hours when ingested orally (even when substantial quantities are consumed). I doubt that the salt would last signifigantly longer. I strongly suspect that the 18-24 hour duration listed is actually refering to 5-meo-amt, a drug that is subjectively substantially different.

---

I removed a purely speculative statement, which said that AMT acts as a stimulant because of "similarities in chemical structure to amphetamine". First of all, it is not that similar; amphetamine is a phenethylamine, and AMT is a tryptamine. Second of all, this drug is an MAOI, which means that it inhibits ALL monoamines to some extent. Third, levels of serotonin (which tryptamines primarily affect) have been shown to have some control over dopamine levels. Lastly, I would just like to say that the edits to this article have unfortunately been dominated by recreational drug users, rather than anyone who knows the first thing about what these drugs do in terms of biochemistry. I'll keep an eye on this article. Fuzzform 02:33, 9 February 2007 (UTC)

[edit] MAOI

AMT and Amphetamine are boths MAOIs because the methyl screws up MAO by getting in the way and taking up its time. —Preceding unsigned comment added by The Right Honourable (talk • contribs) 08:03, August 28, 2007 (UTC)