Alpha-glucan, water dikinase

From Wikipedia, the free encyclopedia

In enzymology, an alpha-glucan, water dikinase (EC 2.7.9.4) is an enzyme that catalyzes the chemical reaction

ATP + alpha-glucan + H₂O AMP + phospho-alpha-glucan + phosphate

The 3 substrates of this enzyme are ATP, alpha-glucan, and H₂O, whereas its 3 products are AMP, phospho-alpha-glucan, and phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with paired acceptors. The systematic name of this enzyme class is ATP:alpha-glucan, water phosphotransferase. This enzyme is also called starch-related R1 protein, GWD.

[edit] References

• IUBMB entry for 2.7.9.4
• BRENDA references for 2.7.9.4 (Recommended.)
• PubMed references for 2.7.9.4
• PubMed Central references for 2.7.9.4
• Google Scholar references for 2.7.9.4
• Ritte G, Lloyd JR, Eckermann N, Rottmann A, Kossmann J, Steup M (2002). "The starch-related R1 protein is an alpha -glucan, water dikinase". Proc. Natl. Acad. Sci. U. S. A. 99: 7166–71. PMID 12011472. 
• Ritte G, Heydenreich M, Mahlow S, Haebel S, Kotting O, Steup M (2006). "Phosphorylation of C6- and C3-positions of glucosyl residues in starch is catalysed by distinct dikinases". FEBS. Lett. 580: 4872–6. PMID 16914145. 

[edit] External links

The CAS registry number for this enzyme class is 664327-94-0.

• IUBMB entry for 2.7.9.4

• KEGG entry for 2.7.9.4

• BRENDA entry for 2.7.9.4

• NiceZyme view of 2.7.9.4

• EC2PDB: PDB structures for 2.7.9.4

• PRIAM entry for 2.7.9.4

• PUMA2 entry for 2.7.9.4

• IntEnz: Integrated Enzyme entry for 2.7.9.4

• MetaCyc entry for 2.7.9.4

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050521: alpha-glucan, water dikinase

• AMIGO entry for GO code 0050521: alpha-glucan, water dikinase