Alkylhalidase

From Wikipedia, the free encyclopedia

In enzymology, an alkylhalidase (EC 3.8.1.1) is an enzyme that catalyzes the chemical reaction

bromochloromethane + H₂O formaldehyde + bromide + chloride

Thus, the two substrates of this enzyme are bromochloromethane and H₂O, whereas its 3 products are formaldehyde, bromide, and chloride.

This enzyme belongs to the family of hydrolases, specifically those acting on halide bonds in carbon-halide compounds. The systematic name of this enzyme class is alkyl-halide halidohydrolase. Other names in common use include halogenase, haloalkane halidohydrolase, and haloalkane dehalogenase.

[edit] References

• IUBMB entry for 3.8.1.1
• BRENDA references for 3.8.1.1 (Recommended.)
• PubMed references for 3.8.1.1
• PubMed Central references for 3.8.1.1
• Google Scholar references for 3.8.1.1
• Heppel LA and Porterfield VT (1948). "Enzymatic dehalogenation of certain brominated and chlorinated compounds". J. Biol. Chem. 176: 763–769. 

[edit] External links

The CAS registry number for this enzyme class is 9025-22-3.

• IUBMB entry for 3.8.1.1

• KEGG entry for 3.8.1.1

• BRENDA entry for 3.8.1.1

• NiceZyme view of 3.8.1.1

• EC2PDB: PDB structures for 3.8.1.1

• PRIAM entry for 3.8.1.1

• PUMA2 entry for 3.8.1.1

• IntEnz: Integrated Enzyme entry for 3.8.1.1

• MetaCyc entry for 3.8.1.1

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047651: alkylhalidase

• AMIGO entry for GO code 0047651: alkylhalidase