Alkenylglycerophosphoethanolamine hydrolase

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In enzymology, an alkenylglycerophosphoethanolamine hydrolase (EC 3.3.2.5) is an enzyme that catalyzes the chemical reaction

1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine + H₂O an aldehyde + sn-glycero-3-phosphoethanolamine

Thus, the two substrates of this enzyme are 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine and H₂O, whereas its two products are aldehyde and sn-glycero-3-phosphoethanolamine.

This enzyme belongs to the family of hydrolases, specifically those acting on ether bonds (ether hydrolases). The systematic name of this enzyme class is 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine aldehydohydrolase. This enzyme participates in ether lipid metabolism.

[edit] References

• IUBMB entry for 3.3.2.5
• BRENDA references for 3.3.2.5 (Recommended.)
• PubMed references for 3.3.2.5
• PubMed Central references for 3.3.2.5
• Google Scholar references for 3.3.2.5
• Gunawan J, Debuch H (1981). "Liberation of free aldehyde from 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine (lysoplasmalogen) by rat liver microsomes". Hoppe. Seylers. Z. Physiol. Chem. 362: 445–52. PMID 7239443. 

[edit] External links

The CAS registry number for this enzyme class is 78413-08-8.

• IUBMB entry for 3.3.2.5

• KEGG entry for 3.3.2.5

• BRENDA entry for 3.3.2.5

• NiceZyme view of 3.3.2.5

• EC2PDB: PDB structures for 3.3.2.5

• PRIAM entry for 3.3.2.5

• PUMA2 entry for 3.3.2.5

• IntEnz: Integrated Enzyme entry for 3.3.2.5

• MetaCyc entry for 3.3.2.5

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047409: alkenylglycerophosphoethanolamine hydrolase

• AMIGO entry for GO code 0047409: alkenylglycerophosphoethanolamine hydrolase