Alkan-1-ol dehydrogenase (acceptor)

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In enzymology, an alkan-1-ol dehydrogenase (acceptor) (EC 1.1.99.20) is an enzyme that catalyzes the chemical reaction

primary alcohol + acceptor $\rightleftharpoons$ aldehyde + reduced acceptor

Thus, the two substrates of this enzyme are primary alcohol and acceptor, whereas its two products are aldehyde and reduced acceptor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is alkan-1-ol:acceptor oxidoreductase. Other names in common use include polyethylene glycol dehydrogenase, and alkan-1-ol:(acceptor) oxidoreductase. This enzyme participates in fatty acid metabolism. It employs one cofactor, PQQ.

[edit] References

IUBMB entry for 1.1.99.20
BRENDA references for 1.1.99.20 (Recommended.)
PubMed references for 1.1.99.20
PubMed Central references for 1.1.99.20
Google Scholar references for 1.1.99.20
Kawai F, Kimura T, Tani Y, Yamada H, Ueno T and Fukami H (1983). "Identification of reaction-products of polyethylene-glycol dehydrogenase". Agric. Biol. Chem. 47: 1669–1671.
and Adachi O (1985). "Identification of the prosthetic group and further characterization of a novel enzyme, polyethylene-glycol dehydrogenase". Agric. Biol. Chem. 49: 1071–1076.